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In the present work, the effects of rosemary extract on xenograft tumor growth has been studied and, for the first time, a shotgun proteomic analysis based on nanoliquid chromatography−tandem mass spectrometry (nano-LC−MS/MS) together with stable isotope dimethyl labeling (DML) has been applied to i...
ORGANISM(S): Homo sapiens (Human) 
2017-04-10 | PXD005853 | Pride
A proteomics strategy based on nano-liquid chromatography-tandem mass spectrometry (nano-LC-MS/MS) using an Orbitrap high-resolution mass spectrometer together with stable isotope dimethyl labeling (DML) is applied to quantitatively examine relative changes in the protein fraction of HT-29 human col...
ORGANISM(S): Homo sapiens (Human) 
2016-06-08 | PXD003623 | Pride
Supercritical rosemary extract (containing 16.90% carnosic acid, 1.90% carnosol and 13.59% volatile compounds) showed antitumor activity on colon cancer cells in vitro. We treated colon cancer cells with the extract and we employed whole genome microarray expression profiling to identify genes poten...
ORGANISM(S): Homo sapiens 
Carnosic acid in topical rosemary extract promotes TRPA1-mediated scarless wound healing
We used Affymetrix microarrays to investigate gene expression changes in the liver of lean female Zucker rats exposed to a normal diet supplemented with a rosemary extract rich in the diterpenic compound, carnosic acid (CA). The aim of this work was to determine whether the daily intake (with the st...
ORGANISM(S): Rattus norvegicus 
Mammalian skin wounds typically heal with a scar, characterized by fibrotic tissue that disrupts original tissue architecture and function. Therapies to reduce fibrosis and scar formation remain a large unmet clinical need. Rosemary extract, particularly in the form of topical oils and creams, has g...
ORGANISM(S): Mus musculus 
2025-10-15 | GSE298490 | GEO
Supercritical rosemary extract (containing 16.90% carnosic acid, 1.90% carnosol and 13.59% volatile compounds) showed antitumor activity on colon cancer cells in vitro. We treated colon cancer cells with the extract and we employed whole genome microarray expression profiling to identify genes poten...
ORGANISM(S): Homo sapiens 
2014-04-04 | GSE56496 | GEO
We used Affymetrix microarrays to investigate gene expression changes in the liver of lean female Zucker rats exposed to a normal diet supplemented with a rosemary extract rich in the diterpenic compound, carnosic acid (CA).
ORGANISM(S): Rattus norvegicus 
2013-09-15 | GSE48373 | GEO
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