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Smoking cessation is the most effective measure for reducing the risk of smoking-related diseases but switching to less harmful products (modified-risk tobacco products) can be an alternative for smokers who would otherwise not quit. In an 18-month chronic carcinogenicity/toxicity study in A/J mice ...
ORGANISM(S): Mus musculus (Mouse) 
2020-08-13 | PXD016460 | Pride
The main constituents of electronic cigarette liquids are nicotine, propylene glycol (PG), and vegetable glycerin (VG), together with distilled water and flavors. To assess the toxicity of PG/VG mixtures with and without nicotine as basic components of liquids used in e-cigarettes, a 90-day rat inha...
ORGANISM(S): Rattus norvegicus (Rat) 
2017-09-11 | PXD006894 | Pride
Aiming to reduce smoking-related health risks, potential reduced risk products (pRRPs) are being developed. The Tobacco Heating System (THS) 2.2 is a recently developed pRRP, which utilizes the heat-not-burn principle. In this study, systems toxicology approaches were engaged to assess the respirato...
ORGANISM(S): Rattus norvegicus (Rat) 
2016-12-12 | PXD003580 | Pride
Aiming to reduce smoking-related health risks, potential reduced risk products (pRRPs) are being developed. The Tobacco Heating System (THS) 2.2 is a recently developed pRRP, which utilizes the heat-not-burn principle. In this study, systems toxicology approaches were engaged to assess the respirato...
ORGANISM(S): Rattus norvegicus (Rat) 
2016-12-13 | PXD003591 | Pride
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