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TranscriptomicsTranscription profiling by array of human B cells from patients with chronic lymphocytic leukemia after co-culture with nurse-like cells
In the marrow and lymphatic tissues, chronic lymphocytic leukemia (CLL) cells interact with accessory cells that constitute the leukemia microenvironment. In lymphatic tissues, CLL cells are interspersed with CD68+ nurselike cells (NLC) and T cells. However, the mechanism regulating co-localization ...
ORGANISM(S): Homo sapiens 
2009-01-13 | E-GEOD-13811 | biostudies-arrayexpress
GenomicsMINCR is a MYC-induced lncRNA able to modulate MYC’s transcriptional network in Burkitt lymphoma cells
Despite the established role of the transcription factor MYC in cancer, little is known about the involvement of lncRNAs in mediating MYC’s function. Here we have intersected RNA-sequencing data from MYC-inducible cell lines, from a cohort of 91 mature B-cell lymphomas and from sorted germinal-cente...
EGAS00001001199 | EGA
TranscriptomicsTranscriptional profiling of 29 cases of diffuse large B cell lymphoma
29 cases of RCHOP treated DLBCL were profiled for gene expression. Different integrated annalysis were performed, including mirNA differential expression between cases classified according to the COO signature (see later) and correlation tests between gene and miRNA expression. After transcriptional...
ORGANISM(S): Homo sapiens 
2011-08-01 | E-GEOD-21846 | biostudies-arrayexpress
TranscriptomicsmiRNA profiling of 36 cases of diffuse large B cell lymphoma
miRNA expression data from 36 cases of RCHOP treated DLBCL samples were correlated with clinical variables in order to find miRNA signatures related with outcome. Cases classified according to the cell of origin classsifer (Wright G, Tan B, Rosenwald A, Hurt EH, Wiestner A, Staudt LM. A gene express...
ORGANISM(S): Homo sapiens 
2011-08-01 | E-GEOD-21848 | biostudies-arrayexpress
UnknownInhibition of focal adhesion kinase overcomes resistance of mantle cell lymphoma to ibrutinib in the bone marrow microenvironment.
Not available
S-EPMC5777199 | biostudies-literature
UnknownAutophagy in Saccharomyces cerevisiae requires the monomeric GTP-binding proteins, Arl1 and Ypt6.
Not available
S-EPMC5079543 | biostudies-literature
TranscriptomicsmiRNA profiling of 29 cases of diffuse large B cell lymphoma
29 cases of RCHOP treated DLBCL were profiled for miRNA expression. Different integrated annalysis were performed, including mirNA differential expression between cases classified according to the COO signature (see later) and correlation tests between gene and miRNA expression. Cases classified acc...
ORGANISM(S): Homo sapiens 
2011-08-01 | E-GEOD-21847 | biostudies-arrayexpress
UnknownCCL3 chemokine expression by chronic lymphocytic leukemia cells orchestrates the composition of the microenvironment in lymph node infiltrates.
Not available
S-EPMC6699159 | biostudies-literature
UnknownAn antibody targeting high-molecular-weight kininogen blocks contact system activation in a model of polymicrobial sepsis.
Not available
S-EPMC12422282 | biostudies-literature
UnknownKnockdown of circulating C1 inhibitor induces neurovascular impairment, glial cell activation, neuroinflammation, and behavioral deficits.
Not available
S-EPMC6551624 | biostudies-literature
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