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UnknownGlycolysis-enhancing α1-adrenergic antagonists modify cognitive symptoms related to Parkinson's disease.
Not available
S-EPMC9981768 | biostudies-literature
TranscriptomicsTranscription profiling of Lotus japonicus grown under different salt acclimation regimes
Model legume Lotus japonicus was subjected to non-lethal long-term salinity and profiled at the transcriptomic level. Three independent experiments were performed, testing two experimental designs: a traditional gradual acclimation following a step-wise increase of salt concentration and an initial ...
ORGANISM(S): Lotus japonicus 
2008-07-17 | E-MEXP-1204 | biostudies-arrayexpress
TranscriptomicsPost-weaning selenium and folate supplementation affects gene and protein expression and global DNA methylation in mice fed high-fat diets
Background: Consumption of high fat diets has negative impacts on health and well-being, some of which may be epigenetically regulated. Selenium and folate are two compounds which influence epigenetic mechanisms. We investigated the hypothesis that post-weaning supplementation with adequate levels o...
ORGANISM(S): Mus musculus 
2013-06-01 | E-GEOD-43038 | biostudies-arrayexpress
GenomicsNational Eye Institute (NEI) Age-Related Eye Disease Study (AREDS)

The Age-Related Eye Disease Study (AREDS) was initially designed as a long-term multi-center, prospective study of the clinical course of age-related macular degeneration (AMD) and age-related cataract. In addition to collecting natural history data, AREDS included a clinical trial of h...

phs000001.v3.p1 | EGA
TranscriptomicsEffects of dietary curcumin on the colon proteome and transcriptome in the Mdr1a-/- mouse model of inflammatory bowel disease
This study assessed gene expression changes associated with inflammation in the colon tissue of multi-drug resistance targeted mutation (Mdr1a-/-) mice, a model of human IBD. It also tested the anti-inflammatory potential of curcumin in the colon of these mice with a particular focus on the proteome...
ORGANISM(S): Mus musculus 
2014-10-02 | E-GEOD-61939 | biostudies-arrayexpress
TranscriptomicsControl of Virulence Gene Expression in Citrobacter rodentium by Trascription Factor RegA
Identification of the targets of RegA with and without bicarbonate stimulation by comparing RegA knockout to multicopy RegA transgenics. RegA is an AraC like transcription factor identified in a mutational screen for virulence genes in Citrobacter rodentium, an attaching and effacing pathogen that ...
ORGANISM(S): Citrobacter rodentium 
2010-05-19 | E-GEOD-12876 | biostudies-arrayexpress
TranscriptomicsModulation of colonic inflammation in Mdr1a-/- mice by green tea polyphenols and their effects on the colon transcriptome and proteome
This study tested the anti-inflammatory potential of a green tea extract rich in polyphenols (GrTP) in the colon of the multi-drug resistance targeted mutation (Mdr1a-/-) mouse model of IBD. A colonic histological injury score was determined for each mouse to establish the effect of GrTP on inflamma...
ORGANISM(S): Mus musculus 
2012-10-18 | E-GEOD-41644 | biostudies-arrayexpress
TranscriptomicsAnalysis of the evolutionary adaptation of an AraC-like global regulatory protein in the murine enteric pathogen Citrobacter rodentium
An experiment to test the equivalence of the Citrobacter rodentium RegA and E.Coli SMS 3-5 homologue 8 Conditions (4 Genotypes by 2 treatments) in duplicate. Reference design without dye swaps.
ORGANISM(S): Citrobacter rodentium 
2015-02-19 | E-GEOD-57689 | biostudies-arrayexpress
UnknownThe global epidemiology and health burden of the autism spectrum: findings from the Global Burden of Disease Study 2021.
Not available
S-EPMC11750762 | biostudies-literature
UnknownPartnership for Research on Ebola VACcination (PREVAC): protocol of a randomized, double-blind, placebo-controlled phase 2 clinical trial evaluating three vaccine strategies against Ebola in healthy volunteers in four West African countries.
Not available
S-EPMC7823170 | biostudies-literature
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