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TranscriptomicsSystematic Analysis of Tissue-Restricted miRISCs Reveals a Broad Role for microRNAs in Suppressing Basal Activation of the C. elegans Pathogen Response
Gene regulation by microRNAs (miRNAs) under specific physiological conditions often involves complex interactions between multiple miRNAs and a large number of their targets, as well as coordination with other regulatory mechanisms, limiting the effectiveness of classical genetic methods to identify...
ORGANISM(S): Caenorhabditis elegans 
2012-03-23 | E-GEOD-36419 | biostudies-arrayexpress
GenomicsAn Ancient Transcription Factor Initiates the Burst of piRNA Production During Early Meiosis in Mouse Testes
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Gallus gallus 
2013-03-26 | E-GEOD-44690 | biostudies-arrayexpress
TranscriptomicsLarge numbers of putative miRNAs originate from DNA transposons and are coincident with a large species radiation in bats.
Vesper bats (family Vespertilionidae) experienced a rapid adaptive radiation beginning around 36 mya that resulted in the second most species rich mammalian family. Coincident with that radiation was an initial burst of DNA transposon activity that has continued into the present. Deep sequencing o...
ORGANISM(S): Equus caballus 
2014-05-19 | E-GEOD-47593 | biostudies-arrayexpress
TranscriptomicsComparative genomic hybridization of strains of Leishmania infantum, Leishmania major and Leishmania tarentolae
The genomic DNAs of strains JPCM5 and 263 of L. infantum, strains LV39 and Friedlin of L. major and strains Parrot-TarII and S125 of L. tarentolae were used in comparative genomic hybridizations to reveal the intra-species and inter-species gene content, and to validate L. tarentolae Parrot-TarII ge...
ORGANISM(S): Leishmania tarentolae 
2011-10-20 | E-GEOD-27184 | biostudies-arrayexpress
TranscriptomicsMicroarray profiling, C elegans: Neuronal miRISC IP vs Total RNA
Identifying the physiological functions of microRNAs (miRNAs) is often challenging because miRNAs commonly impact gene expression under specific physiological conditions through complex miRNA::mRNA interaction networks and in coordination with other means of gene regulation, such as transcriptional ...
ORGANISM(S): Caenorhabditis elegans 
2014-01-01 | E-GEOD-45871 | biostudies-arrayexpress
Transcriptomics3'-UTR-seq of female and male mouse pituitary gland across pubertal transition
The pituitary gland exhibits sex differences in its function. Diseases associated with dysregulation of the pituitary are also sex-biased in prevalence. Previous qPCR profiling of puberty-related genes in the pituitary gland revealed increasingly sex-biased expression of genes profiled across pubert...
ORGANISM(S): Mus musculus 
2022-10-12 | E-MTAB-9459 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of hypertensive and hypotensive mice
Hypertension is a condition with major cardiovascular and renal complications, affecting nearly a billion patients worldwide. Few validated gene targets are available for pharmacological intervention, so there is a need to identify new biological pathways regulating blood pressure and containing nov...
ORGANISM(S): Mus musculus 
2010-05-16 | E-GEOD-19817 | biostudies-arrayexpress
UnknownSocializing One Health: an innovative strategy to investigate social and behavioral risks of emerging viral threats.
Not available
S-EPMC8122533 | biostudies-literature
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