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GenomicsOpioid-induced gut microbial disruption leads to gut barrier compromise and sustained systemic inflammation.
Morphine and its pharmacological derivatives are the most prescribed analgesics for moderate to severe pain management. However, chronic use of morphine reduces pathogen clearance and induces bacterial translocation across the gut barrier. The enteric microbiome has been shown to play a critical rol...
ORGANISM(S): Mus musculus domesticus 
2016-06-01 | E-MTAB-3722 | biostudies-arrayexpress
GenomicsEffect of morphine treatment on microbiome in the context of microbial transplant.
Morphine causes microbial dysbiosis. In this study we focused on restoration of native microbiota in morphine treated mice and looked at the extent of restoration and immunological consequences of this restoration. Fecal transplant has been successfully used clinically, especially for treating C. di...
ORGANISM(S): Mus musculus domesticus 
2016-06-01 | E-MTAB-3723 | biostudies-arrayexpress
UnknownDifferential effects of gram-positive and gram-negative bacterial products on morphine induced inhibition of phagocytosis.
Not available
S-EPMC4759540 | biostudies-literature
UnknownCore-Shell Nanofibrous Scaffold Based on Polycaprolactone-Silk Fibroin Emulsion Electrospinning for Tissue Engineering Applications.
Not available
S-EPMC6164798 | biostudies-literature
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