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UnknownTargeting RPS6KC1 to overcome enzalutamide resistance in prostate cancer.
Not available
S-EPMC12375275 | biostudies-literature
ProteomicsBiallelic variants in the ribosomal protein RPS6KC1 cause a complex neurodevelopmental disorder
The ribosomal protein S6 kinase family members play essential biological functions in disease, from cancer to intellectual disability. Little is known about RPS6KC1, aside from its lack of phosphorylation capacity and its roles in sphingosine-1-phosphate signaling and peroxiredoxin-3 transport to mi...
ORGANISM(S): Homo sapiens (Human) 
2025-09-25 | PXD065493 | Pride
Dia Tmt Sphingosine Pi(3)p Rps6kc1 Neurodevelopmental delay Rsk family Mtor Label free 
UnknownA Multibreed Genome-Wide Association Study for Cattle Leukocyte Telomere Length.
Not available
S-EPMC10454124 | biostudies-literature
UnknownWhole-exome sequencing combined with functional genomics reveals novel candidate driver cancer genes in endometrial cancer.
Not available
S-EPMC3483541 | biostudies-literature
TranscriptomicsWT and Mk2/3 KO MEFs response to etoposide
Primary mouse embryonic fibroblasts (MEFs) from wt and MK2/3 KO mice were treated with 20µM etoposide. Primary MEFs from wt and MK2/3 KO mice were treated with 20µM etoposide and RNA extracted after 1h and 6h.
ORGANISM(S): Mus musculus 
2015-04-07 | E-GEOD-67266 | biostudies-arrayexpress
UnknownGenome-Wide Association Study to Identify Susceptibility Loci That Modify Radiation-Related Risk for Breast Cancer After Childhood Cancer.
Not available
S-EPMC6059172 | biostudies-literature
GenomicsWhole-exome Sequencing Combined with Functional Genomics Reveals Novel Candidate Driver Cancer Genes in Endometrial Cancer
Endometrial cancer is the most common gynecological malignancy, with more than 280,000 cases occurring annually worldwide. Although previous studies have identified important common somatic mutations in endometrial cancer, they have primarily focused on a small set of known cancer genes and have thu...
EGAS00001000318 | EGA
TranscriptomicsInfection of MK2 cells with monkeypox virus
Orthopox viruses, including monkeypox, multiply intracellularly and induce numerous changes in host genes expression. The virus target mainly humoral host response, and simultaneously, exploits other genes and functions to reproduce effectively. The goal of this experiment is to identify those hos...
ORGANISM(S): Macaca mulatta 
2010-04-07 | E-GEOD-21001 | biostudies-arrayexpress
TranscriptomicsAnalysis of the senescent transcriptome upon expression of a ZFP36L1 phosphomutant
We expressed either a wt or a phosphomutant version of ZFP36L1 in IMR90 ER:RAS cells. 7 days upon RAS induction (when the cells reach a fully senescent phenotype) we collected the RNA. ZFP36L1 is a RNA binding protein that binds to AU-rich elements in the 3’UTR of mRNAs and triggers their degradat...
ORGANISM(S): Homo sapiens 
2015-07-07 | E-GEOD-61130 | biostudies-arrayexpress
ProteomicsQuantitative In Vivo Proteomics of Metformin Response in Liver Reveals AMPK-Dependent and -Independent Signaling Networks
Metformin is the front-line treatment for type 2 diabetes worldwide. It acts via effects on glucose and lipid metabolism in metabolic tissues, leading to enhanced insulin sensitivity. Despite significant effort, the molecular basis for metformin response remains poorly understood, with a limited nu...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2019-10-07 | MSV000084429 | MassIVE
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