Sort   by:  
 Page size 
ProteomicsNanobody-mediated modulation of long RSH enzymes Rel and RelA catalysis by restriction of their conformational landscape
Long RSH enzymes, Rel and RelA, are the master regulators of (p)ppGpp alarmone levels in bacteria. Their catalytic activity is governed by transitions between a compact, hydrolysis-competent (HDON) state and an elongated, synthesis-competent (SYNTHON) state. The equilibrium between these states is m...
ORGANISM(S): Escherichia coli 
2026-04-28 | PXD067451 | Pride
Structural biology Rsh enzymes Nanobodies 
UnknownRSH enzyme diversity for (p)ppGpp metabolism in Phaeodactylum tricornutum and other diatoms.
Not available
S-EPMC6881373 | biostudies-literature
UnknownIdentification of an rsh gene from a Novosphingobium sp. necessary for quorum-sensing signal accumulation.
Not available
S-EPMC2668395 | biostudies-literature
UnknownThe (p)ppGpp Synthetase RSH Mediates Stationary-Phase Onset and Antibiotic Stress Survival in Clostridioides difficile.
Not available
S-EPMC7484180 | biostudies-literature
UnknownThe RelA/SpoT homolog (RSH) superfamily: distribution and functional evolution of ppGpp synthetases and hydrolases across the tree of life.
Not available
S-EPMC3153485 | biostudies-literature
TranscriptomicsExpression analysis of Saccharomyces cerevisiae INVSc1 under accumulation of the bacterial alarmone ppGpp
ppGpp accumulation caused by ectopic expression of RelA in Saccharomyces cerevisiae gave rise to marked changes in gene expression with both upregulation and downregulation, including changes in mitochondrial gene expression. The most prominent upregulation (38-fold) was detected in the function-unk...
ORGANISM(S): Saccharomyces cerevisiae 
2012-05-30 | E-GEOD-38239 | biostudies-arrayexpress
UnknownTranscriptome Analysis of Novosphingobium pentaromativorans US6-1 Reveals the Rsh Regulon and Potential Molecular Mechanisms of N-acyl-l-homoserine Lactone Accumulation.
Not available
S-EPMC6163740 | biostudies-literature
UnknownMethylobacterium extorquens RSH Enzyme Synthesizes (p)ppGpp and pppApp in vitro and in vivo, and Leads to Discovery of pppApp Synthesis in Escherichia coli.
Not available
S-EPMC6491832 | biostudies-literature
UnknownThe C-Terminal RRM/ACT Domain Is Crucial for Fine-Tuning the Activation of 'Long' RelA-SpoT Homolog Enzymes by Ribosomal Complexes.
Not available
S-EPMC7058999 | biostudies-literature
UnknownAPOBEC Enzymes: Mutagenic Fuel for Cancer Evolution and Heterogeneity.
Not available
S-EPMC4497973 | biostudies-literature
Sort   by:  
 Page size