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ProteomicsInducible degradation-coupled phosphoproteomics identifies PP2A-Rts1 as a novel eisosome regulator
We developed and validated a workflow in S. cerevisiae combining auxin-inducible protein degradation with LC-MS/MS phosphoproteomics and used it to identify candidate phosphatase substrates during mitosis, when kinase activity is high. Our results revealed that PP2A-Rts1 influences dephosphorylation...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2023-10-24 | PXD044337 | Pride
Phosphoproteomics Pp2a Rts1 Phosphatase Auxin inducible degradation 
GenomicsRtf2 is Important for Replication Fork Barrier Activity of RTS1 via Splicing of Rtf1 [Pu-Seq]
Rtf2 is Important for Replication Fork Barrier Activity of RTS1 via Splicing of Rtf1 [Pu-Seq]
PRJNA791219 | ENA
ProteomicsPP2A-Rts1 antagonizes Rck2-mediated hyperosmotic stress signaling in yeast
In Saccharomyces cerevisiae impairment of protein phosphatase PP2A-Rts1 leads to temperature and hyperosmotic stress sensitivity, yet the underlying mechanism and the scope of action of the phosphatase in the stress response remain elusive. Using quantitative mass spectrometry-based approaches we ha...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2022-05-16 | PXD019647 | Pride
Rck2 Stress response Phosphorylation Hyperosmotic stress Hog1 Phosphatase Pp2a Stress signaling Saccharomyces cerevisiae Rts1 Quantitative proteomics 
GenomicsRtf2 is Important for Replication Fork Barrier Activity of RTS1 via Splicing of Rtf1 [cDNA-Seq]
Rtf2 is Important for Replication Fork Barrier Activity of RTS1 via Splicing of Rtf1 [cDNA-Seq]
PRJNA791218 | ENA
OtherRtf2 is Important for Replication Fork Barrier Activity of RTS1 via Splicing of Rtf1 [cDNA-Seq]
This study investigated the role Rtf2 plays on the replication fork barrier (RFB) activity of RTS1 in S. pombe. We confirm Rtf2 is important for the full barrier activity of the RTS1-Rtf1 RFB. We show that Rtf2 does not enact its enhancing effect on RTS1 RFB activity via binding to Region A of RTS1,...
ORGANISM(S): Schizosaccharomyces pombe 
2021-12-24 | GSE192343 | GEO
OtherRtf2 is Important for Replication Fork Barrier Activity of RTS1 via Splicing of Rtf1 [Pu-Seq]
This study investigated the role Rtf2 plays on the replication fork barrier (RFB) activity of RTS1 in S. pombe. We confirm Rtf2 is important for the full barrier activity of the RTS1-Rtf1 RFB. We show that Rtf2 does not enact its enhancing effect on RTS1 RFB activity via binding to Region A of RTS1,...
ORGANISM(S): Schizosaccharomyces pombe 
2021-12-24 | GSE192342 | GEO
UnknownComplete nucleotide sequence of plasmid Rts1: implications for evolution of large plasmid genomes.
Not available
S-EPMC135101 | biostudies-literature
UnknownYeast Lacking the PP2A Phosphatase Regulatory Subunit Rts1 Sensitizes rad51 Mutants to Specific DNA Damaging Agents.
Not available
S-EPMC6857479 | biostudies-literature
UnknownA comprehensive list of genes required for the efficient conjugation of plasmid Rts1 was determined by systematic deletion analysis.
Not available
S-EPMC10838148 | biostudies-literature
UnknownThe Rts1 regulatory subunit of protein phosphatase 2A is required for control of G1 cyclin transcription and nutrient modulation of cell size.
Not available
S-EPMC2770260 | biostudies-literature
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