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MetabolomicsProteomic analysis of osteocyte line (MLO-Y4) with knockout of cystic fibrosis transmembrane conductance regulator (CFTR) or chloride deprivation treatment

Mass spectrometry–based proteomic analysis of an osteocyte line, MLO-Y4, was conducted to profile global protein expression changes under two experimental settings, 1) CRISPR-Cas9-based knockout of CFTR versus wild-type; 2) Cl- deprivation versus normal extracellular medium.

2026-03-27 | MTBLS14165 | MetaboLights
UnknownDistinct Aging-Vulnerable and -Resilient Trajectories of Specific Motor Circuit Functions in Oxidation- and Temperature-Stressed Drosophila.
Not available
S-EPMC8805199 | biostudies-literature
ProteomicsLactylation of NAT10 promotes N4‐acetylcytidine modification on tRNASer-CGA-1-1 to boost oncogenic DNA virus KSHV reactivation
N4-acetylcytidine (ac4C), a conserved but recently rediscovered RNA modification on tRNAs, rRNAs and mRNAs, is catalyzed by N-acetyltransferase 10 (NAT10). Lysine acylation is a ubiquitous protein modification that controls protein functions. Our latest study demonstrates a NAT10-dependent ac4C modi...
ORGANISM(S): Homo Sapiens 
2024-04-26 | PXD049447 |
UnknownAssociation of Germline Single Nucleotide Polymorphisms in Steroid Hormone Metabolism Pathway With Androgen Deprivation Therapy Prognosis of Prostate Cancer in Chinese Population.
Not available
S-EPMC12579894 | biostudies-literature
UnknownProfile of biological aging in first primary cancers: a pan-cancer analysis of two large-scale cohorts from the UK and Hong Kong.
Not available
S-EPMC12538744 | biostudies-literature
UnknownMRI T2w Radiomics-Based Machine Learning Models in Imaging Simulated Biopsy Add Diagnostic Value to PI-RADS in Predicting Prostate Cancer: A Retrospective Diagnostic Study.
Not available
S-EPMC11394278 | biostudies-literature
UnknownGRPR-induced FAM135A expression promote perineural invasion in prostate cancer.
Not available
S-EPMC12625755 | biostudies-literature
UnknownComparison of systematic and combined biopsy for the detection of prostate cancer.
Not available
S-EPMC11449415 | biostudies-literature
Unknownphi and phiD predict adverse pathological features after radical prostatectomy for prostate cancer in Chinese population.
Not available
S-EPMC11310664 | biostudies-literature
UnknownCost-effectiveness analysis of prostate-specific antigen screening in China: a middle-income population-based microsimulation study.
Not available
S-EPMC12465055 | biostudies-literature
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