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To identify cooperating lesions in core-binding-factor acute myeloid leukemia (CBF-AML), we performed single-nucleotide polymorphism (SNP)-array analysis on 300 diagnostic and 41 relapse adult and pediatric leukemia samples. We identified a mean of 1.28 copy number alterations (CNAs) per case at dia...
ORGANISM(S): Homo sapiens 

We have performed whole genome sequencing of 4 cases of pediatric acute megakaryoblastic leukemia to identify somatic genetic alterations driving leukemogenesis.

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