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ProteomicsCLUH controls astrin-1 expression to couple mitochondrial metabolism to cell cycle progression
Proliferating cells undergo metabolic changes in synchrony with cell cycle progression and cell division. Mitochondria provide fuel, metabolites, and ATP during different phases of the cell cycle, however it is not completely understood how mitochondrial function and the cell cycle are coordinated. ...
ORGANISM(S): Homo sapiens (Human) 
2022-05-30 | PXD029145 | Pride
Cluh  spag5  mitochondria 
ProteomicsCLUH controls astrin-1 expression to couple mitochondrial metabolism to cell cycle progression
Proliferating cells undergo metabolic changes in synchrony with cell cycle progression and cell division. Mitochondria provide fuel, metabolites, and ATP during different phases of the cell cycle, however it is not completely understood how mitochondrial function and the cell cycle are coordinated. ...
ORGANISM(S): Homo sapiens (Human) 
2022-05-30 | PXD029142 | Pride
Cluh  spag5  mitochondria 
ProteomicsCLUH controls astrin-1 expression to couple mitochondrial metabolism to cell cycle progression
Proliferating cells undergo metabolic changes in synchrony with cell cycle progression and cell division. Mitochondria provide fuel, metabolites, and ATP during different phases of the cell cycle, however it is not completely understood how mitochondrial function and the cell cycle are coordinated. ...
ORGANISM(S): Homo sapiens (Human) 
2022-05-30 | PXD029156 | Pride
Cluh  spag5  mitochondria 
ProteomicsERLIN1 and ERLIN2 scaffolds bridge TMUB1 and RNF170 and restrict cholesterol esterification to regulate the secretory pathway
Complexes of ERLIN1 and ERLIN2 form large ring-like cup shaped structures on the endoplasmic reticulum (ER) membrane and serve as platform to bind cholesterol and E3-ubiquitin ligases, potentially defining functional nanodomains. Here, we show that ERLIN scaffolds mediate the interaction between the...
ORGANISM(S): Homo sapiens (Human) 
2024-05-21 | PXD048503 | Pride
Erlin2 Tmub1 Drms Endoplasmic reticulum Hereditary spastic paraplegia Erlin1 Lipid rafts 
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