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ProteomicsCLUH controls astrin-1 expression to couple mitochondrial metabolism to cell cycle progression
Proliferating cells undergo metabolic changes in synchrony with cell cycle progression and cell division. Mitochondria provide fuel, metabolites, and ATP during different phases of the cell cycle, however it is not completely understood how mitochondrial function and the cell cycle are coordinated. ...
ORGANISM(S): Homo sapiens (Human) 
2022-05-30 | PXD029145 | Pride
Cluh  spag5  mitochondria 
ProteomicsCLUH interactome reveals its association to SPAG5 and its proximity to the translation of mitochondrial proteins
Mitochondria require thousands of proteins to fulfil their essential function in energy production and other fundamental biological processes. These proteins are mostly encoded by the nuclear genome, translated in the cytoplasm before being imported into the organelle. RNA binding proteins (RBPs) ar...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2021-12-13 | PXD027158 | Pride
Cluh Turboid Rna binding protein Mitochondrial proteins Bioid 
ProteomicsCLUH controls astrin-1 expression to couple mitochondrial metabolism to cell cycle progression
Proliferating cells undergo metabolic changes in synchrony with cell cycle progression and cell division. Mitochondria provide fuel, metabolites, and ATP during different phases of the cell cycle, however it is not completely understood how mitochondrial function and the cell cycle are coordinated. ...
ORGANISM(S): Homo sapiens (Human) 
2022-05-30 | PXD029142 | Pride
Cluh  spag5  mitochondria 
ProteomicsCLUH controls astrin-1 expression to couple mitochondrial metabolism to cell cycle progression
Proliferating cells undergo metabolic changes in synchrony with cell cycle progression and cell division. Mitochondria provide fuel, metabolites, and ATP during different phases of the cell cycle, however it is not completely understood how mitochondrial function and the cell cycle are coordinated. ...
ORGANISM(S): Homo sapiens (Human) 
2022-05-30 | PXD029156 | Pride
Cluh  spag5  mitochondria 
ProteomicsCLUH-dependent RNA granules coordinate mitochondrial catabolic pathways with mTORC1 signaling and mitophagy
Mitochondria house anabolic and catabolic processes that must be balanced and rapidly adjusted to meet the cellular demands. CLUH binds mRNAs of nuclear encoded mitochondrial proteins and is highly expressed in the liver, where it regulates metabolic plasticity by an ill-defined mechanism. Here, we ...
ORGANISM(S): Mus musculus (Mouse) 
2020-03-19 | PXD014098 | Pride
Mitochondria Catabolism Rna-binding proteins 
UnknownCluh plays a pivotal role during adipogenesis by regulating the activity of mitochondria.
Not available
S-EPMC6497719 | biostudies-literature
UnknownCLUH granules coordinate translation of mitochondrial proteins with mTORC1 signaling and mitophagy.
Not available
S-EPMC7196838 | biostudies-literature
UnknownCLUH maintains functional mitochondria and translation in motoneuronal axons and prevents peripheral neuropathy.
Not available
S-EPMC11135423 | biostudies-literature
UnknownCLUH controls astrin-1 expression to couple mitochondrial metabolism to cell cycle progression.
Not available
S-EPMC9135405 | biostudies-literature
UnknownCLUH regulates mitochondrial metabolism by controlling translation and decay of target mRNAs.
Not available
S-EPMC5350512 | biostudies-literature
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