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TranscriptomicsFemale sex and oestrogen receptor β attenuate cardiac remodelling and apoptosis in pressure overload
Aims: We investigate sex differences and the role of oestrogen receptor beta (ERbeta) in a mouse model of pressure overload-induced myocardial hypertrophy. Methods and results: We performed transverse aortic constriction (TAC) or sham surgery in male and female wild-type (WT) and ER knockout (ERbet...
ORGANISM(S): Mus musculus 
2010-01-19 | E-GEOD-18224 | biostudies-arrayexpress
ModelsSaldivar2024 - iAS473 - Methylacidiphilum fumariolicum - GEM
Genome Scale metabolic model of M. fumariolicum strain Pic
2024-02-05 | MODEL2308220001 | BioModels
ProteomicsA serum proteomic signature predictive of flare during biologic tapering in rheumatoid arthritis
Rheumatoid arthritis (RA) is a chronic immune-mediated inflammatory disease characterized by joint inflammation, systemic manifestations, and a heterogeneous clinical course marked by periods of remission and disease flares. The introduction of biologic therapies has revolutionized RA treatment by e...
ORGANISM(S): Homo sapiens (Human) 
2026-10-05 | PXD073940 | Pride
Serum proteome Autoantibodies Disease flare Rheumatoid arthritis Biomarkers 
TranscriptomicsWnt & LIF signalling in mESC
The molecular processes underlying the properties of ESC are yet unknown even when it's well established that LIF/STAT3 is neccesary for the maintenance of pluripotency. Other pathways as Wnt are may be implicated in the regulation of the biological mechanisms in mESC. Work model: D3-ES cultivated w...
ORGANISM(S): Mus musculus 
2009-12-30 | E-GEOD-11628 | biostudies-arrayexpress
UnknownStandard versus continuous administration of capecitabine in metastatic breast cancer (GEICAM/2009-05): a randomized, noninferiority phase II trial with a pharmacogenetic analysis.
Not available
S-EPMC4319639 | biostudies-literature
TranscriptomicsSepsis Express IG
The peripheral whole-blood transcriptome analysis has been used to the identification of biomarkers in different clinical syndromes. The ability to simultaneously measure the gene expression levels of the whole transcriptome is providing a broader view of clinical syndromes such as sepsis. The aim o...
ORGANISM(S): Homo sapiens 
2014-03-15 | E-MTAB-1548 | biostudies-arrayexpress
UnknownThe impact of health and wellness coaching on patient-important outcomes in chronic illness care: A systematic review and meta-analysis.
Not available
S-EPMC10964774 | biostudies-literature
TranscriptomicsTranscription profiling of mouse adipocytes after telmisartan, pioglitazone or irbesartan treatment
expression pattern of adipocytes after telmisartan, pioglitazone or irbesartan treatment
ORGANISM(S): Mus musculus 
2008-06-12 | E-GEOD-2486 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of right ventricule from arrhythmogenic heterozygous plakoglobin deficient mice undergone endurance training to identify transcriptional responses to training.
Endurance training accelerated development of right ventricular dysfunction and arrhythmias in plakoglobin+/- mice. Histology and electron microscopy did not identify right ventricular abnormalities. To identify differences in the transcriptional response to training gene expression profiling was pe...
ORGANISM(S): Mus musculus 
2007-11-06 | E-GEOD-4120 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse HDAC2 knockout myocardium
We used microarrays to detail the global programme of gene expression underlying cardiac development by HDAC2 and identified distinct classes of up-regulated and down-regulated genes during this process. Experiment Overall Design: Embryonic heart ventricles were dissected at E17.5 for RNA extraction...
ORGANISM(S): Mus musculus 
2008-06-15 | E-GEOD-6770 | biostudies-arrayexpress
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