Sort   by:  
 Page size 
Transcription termination pathways mitigate the detrimental consequences of unscheduled promiscuous initiation occurring at hundreds of thousands of genomic cis-regulatory elements. The Restrictor complex, composed of the Pol II-interacting protein WDR82 and the RNA-binding protein ZC3H4, suppresses...
ORGANISM(S): Homo sapiens (Human) 
2024-05-23 | PXD043638 | Pride
In this study, we performed the transcriptome analysis of a cohort comprising 72 (20 already published E-MTAB-11599) MTC (medullary thyroid carcinoma) specimens from patients with different genetic background (w/o RET or RAS mutations).
ORGANISM(S): Homo sapiens 
Histone modifying enzymes depend on the availability of cofactors, with acetyl-CoA being required for histone acetyltransferase (HAT) activity. The discovery that mitochondrial acyl-CoA producing enzymes are also delivered to the nucleus suggests that high concentrations of metabolites generated loc...
ORGANISM(S): Mus musculus (Mouse) 
2025-05-06 | PXD040979 | Pride
The transcriptomic dose-dependent response of rat immortalized thyrocytes to two thyroid disrupting chemicals was investigated by RNA-seq experiment. PCCl3 cells were exposed for one week to different doses of ethylenethiourea (ETU) and chlorpyrifos (CPF) and to their combinations.
ORGANISM(S): Rattus norvegicus 
To identify a group of genes, characteristic of a single neoplasia and determinant for the risk to relapse, we have performed gene expression analysis of ductal breast carcinoma samples using Affymetrix oligonucletide microarray (HU133A). Biopses from 60 patients, 30 good prognosis (desease free fro...
ORGANISM(S): Homo sapiens 
Sort   by:  
 Page size