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TranscriptomicsIdentification of androgen-regulated genes in RWPE-1-AR cells
Transcriptional profiling of RWPE-1 cells stably expressing human androgen receptor (as described in Altintas et al., Mol Cell Endocrinol 2011) treated with a non-metabolisable androgen, R1881 RWPE-1-AR cells were treated with R1881 during 3h or 24h and compared to control not treated cells. Three i...
ORGANISM(S): Homo sapiens 
2011-05-12 | E-GEOD-29232 | biostudies-arrayexpress
TranscriptomicsRNA-seq of dihydrotestosterone (DHT) stimulated prostate epithelial cell lines RWPE-1-Ctrl, RWPE-1-AR and prostate cancer cell lines LNCaP-pcDNA3.1 and LNCaP-Arhi
RNA-sequencing from RWPE-Ctrl (empty vector control), RWPE-1-AR (transduced with androgen receptor cDNA), LNCaP-pcDNA3.1 (empty vector control), and LNCaP-ARhi (transfected with androgen receptor cDNA) cells treated with 0, 1, 10, or 100 nM DHT for 4 hours before RNA extraction. Biological triplicat...
ORGANISM(S): Homo sapiens 
2026-07-31 | E-MTAB-15758 | biostudies-arrayexpress
TranscriptomicsATAC-seq of dihydrotestosterone (DHT) stimulated prostate epithelial cell lines RWPE-1-Ctrl, RWPE-1-AR and prostate cancer cell lines LNCaP-pcDNA3.1 and LNCaP-Arhi
ATAC-sequencing from RWPE-Ctrl (empty vector control), RWPE-1-AR (transduced with androgen receptor cDNA), LNCaP-pcDNA3.1 (empty vector control), and LNCaP-ARhi (transfected with androgen receptor cDNA) cells treated with 0, 1, 10, or 100 nM DHT for 2 hours before nuclei isolation. Biological duplic...
ORGANISM(S): Homo sapiens 
2026-07-31 | E-MTAB-15731 | biostudies-arrayexpress
TranscriptomicsExpression profiling of human prostate non-tumorigenic RWPE-1 cells after overexpressing ERG and ETV1, and ERG and ETV1 silencing on prostate cancer cells LNCaP and VCaP, respectively
Chromosomal rearrangements involving ETS factors, ERG and ETV1, occur frequently in prostate cancer. We here examine human prostate non-tumorigenic RWPE-1 cells with ERG- or ETV1-expressing stable RWPE-1 cell. RWPE-1 stable cell clones overexpressing ERG and ETV1 were grown under normal conditions. ...
ORGANISM(S): Homo sapiens 
2013-03-01 | E-GEOD-39353 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of prostate cells with CHD1 knockdown
Gene expression profiling of prostate tumor cells comparing cells that have CHD1 knockdown by shRNA (RWPE-1, OPCN2) or siRNA (LNCaP) with cells treated with non-targeted control. Prostate cell lines had CHD1 knockdown via shRNA or siRNA were hybridized against cells that were targeted with non-targe...
ORGANISM(S): Homo sapiens 
2011-12-19 | E-GEOD-33531 | biostudies-arrayexpress
GenomicsRNA-seq of dihydrotestosterone (DHT) stimulated prostate epithelial cell lines RWPE-1-Ctrl, RWPE-1-AR and prostate cancer cell lines LNCaP-pcDNA3.1 and LNCaP-Arhi
RNA-seq of dihydrotestosterone (DHT) stimulated prostate epithelial cell lines RWPE-1-Ctrl, RWPE-1-AR and prostate cancer cell lines LNCaP-pcDNA3.1 and LNCaP-Arhi
PRJEB100860 | ENA
GenomicsATAC-seq of dihydrotestosterone (DHT) stimulated prostate epithelial cell lines RWPE-1-Ctrl, RWPE-1-AR and prostate cancer cell lines LNCaP-pcDNA3.1 and LNCaP-Arhi
ATAC-seq of dihydrotestosterone (DHT) stimulated prostate epithelial cell lines RWPE-1-Ctrl, RWPE-1-AR and prostate cancer cell lines LNCaP-pcDNA3.1 and LNCaP-Arhi
PRJEB100789 | ENA
TranscriptomicsExpression data from the RWPE-1 prostate epithelial cell line overexpressing the miR-183 family cluster
The full genomic miR-183 cluster (4.8kb) was cloned into lentiviral vector CD511B-1 with polycistronic GFP. RWPE-1 were transduced with a lentivirus from this vector (RWPE-1 183FC), or a CD511B-1 scrambled control with polycistronic GFP (RWPE-1 control). RWPE-1 were FACS sorted by GFP expression and...
ORGANISM(S): Homo sapiens 
2017-05-23 | GSE99134 | GEO
TranscriptomicsGene expression data from immortal and arsenite-transformed malignant prostate epithelial cells
The aim of this study was to determine how gene expression is changed after arsenite-induced malignant transformation of prostate epithelial cells. Gene expression from three distinct passages of untreated, immortal RWPE-1 cells was compared to three timepoints of arsenite-exposed RWPE-1 cells (CAsE...
ORGANISM(S): Homo sapiens 
2013-05-18 | E-GEOD-47047 | biostudies-arrayexpress
TranscriptomicsmiRNA expression in LNCaP, PC3, Du-145 and RWPE-1 cell lines
MiRNAs are small non-coding RNAs that regulate the expression of specific mRNA targets mainly by translational repression, mRNA deadenylation or cleavage. This series is meant to identify miRNAs deregulated in prostate cancer (PCa) by comparing the PCa cell lines LNCaP, PC3 and Du-145 to the normal ...
ORGANISM(S): Homo sapiens 
2012-03-08 | E-GEOD-17317 | biostudies-arrayexpress
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