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ProteomicsIdentification of serum protein biomarkers for pre-cancerous lesions associated with Pancreatic Ductal Adenocarcinoma (Part1: Mouse)
Pancreatic ductal adenocarcinoma (PDAC) has poor prognosis as early-stage asymptomaticity leads to late-stage diagnoses. Strategies to detect PDAC earlier or identify predisposed individuals are therefore paramount. Here we report results from genetically engineered mice (GEMMs) and PDAC patients th...
ORGANISM(S): Mus musculus (Mouse) 
2026-06-15 | PXD065578 | Pride
Autophagy Early detection Serum Mice Biomarker Pancreatic ductal adenocarcinoma  pancreatic intraepithelial neoplasia 
ProteomicsIdentification of serum protein biomarkers for pre-cancerous lesions associated with Pancreatic Ductal Adenocarcinoma (Part3:Human)
Pancreatic ductal adenocarcinoma (PDAC) has poor prognosis as early-stage asymptomaticity leads to late-stage diagnoses. Strategies to detect PDAC earlier or identify predisposed individuals are therefore paramount. Here we report results from genetically engineered mice (GEMMs) and PDAC patients th...
ORGANISM(S): Homo sapiens (Human) 
2026-06-15 | PXD065581 | Pride
Autophagy Early detection Serum Mice Biomarker Pancreatic ductal adenocarcinoma  pancreatic intraepithelial neoplasia 
ProteomicsIdentification of serum protein biomarkers for pre-cancerous lesions associated with Pancreatic Ductal Adenocarcinoma (Part2 : KPC-Mice)
Pancreatic ductal adenocarcinoma (PDAC) has poor prognosis as early-stage asymptomaticity leads to late-stage diagnoses. Strategies to detect PDAC earlier or identify predisposed individuals are therefore paramount. Here we report results from genetically engineered mice (GEMMs) and PDAC patients th...
ORGANISM(S): Mus musculus (Mouse) 
2026-06-15 | PXD065698 | Pride
Autophagy Early detection Serum Biomarker Pancreatic ductal adenocarcinoma  pancreatic intraepithelial neoplasia 
ProteomicsExposure of Aspergillus fumigatus to Klebsiella pneumoniae culture filtrate inhibits growth and stimulates gliotoxin production.
Aspergillus fumigatus is an opportunistic fungal pathogen of the lungs resulting in both chronic and acute infection. The fungus interacts with numerous bacteria that compose the microflora of the lung including Pseudomonas aeruginosa and Klebsiella pneumoniae, both common isolates from Cystic fibro...
ORGANISM(S): Aspergillus fumigatus Af293 
2023-03-11 | PXD037833 | Pride
Aspergillus Proteomics Gliotoxin Klebsiella Polymicrobial interaction 
UnknownA DNA damage-activated kinase phosphorylates a transcriptional repressor to control bacterial immune pathway expression
Not available
S-SCDT-10_1038-S44318-026-00831-Y | biostudies-other
TranscriptomicsIdentification of a complex genetic network involved in Saccharomyces cerevisiae colony morphology
When grown on solid substrates, different microorganisms often form colonies with very specific morphologies. Whereas the pioneers of microbiology often used colony morphology to discriminate between species and strains, the phenomenon has not received much recent attention. In this study, we use ...
ORGANISM(S): Saccharomyces cerevisiae 
2012-04-27 | E-GEOD-36151 | biostudies-arrayexpress
UnknownTrial Design and Objectives for Castration-Resistant Prostate Cancer: Updated Recommendations From the Prostate Cancer Clinical Trials Working Group 3.
Not available
S-EPMC4872347 | biostudies-literature
GenomicsDetermining Genetic Role in Treatment Response to Anti-Platelet Interventions (The PAPI Study)

CHD is the leading cause of death in the United States. One of the most common ways to prevent CHD is to take an anti-platelet agent, which lessens platelet aggregation. Two of the most common anti-platelet agents are aspirin and clopidogrel. However, up to 25% to 30% of people do not r...

phs000391.v1.p1 | EGA
GenomicsChildren's Hospital of Philadelphia (CHOP) Control Copy Number Variation (CNV) Study

We present a database of copy number variations (CNVs) detected in 2,026 disease-free individuals, using high-density, SNP-based oligonucleotide microarrays. This large cohort analyzed for CNVs in a single study using a uniform array platform and computational tools, comprises mainly of Cau...

phs000199.v1.p1 | EGA
TranscriptomicsDiet-induced chromatin remodeling in mice livers
The tissue-specific packaging of the genome into the nucleus through chromatin is fundamentally involved in gene regulation, and aberrant modifications to chromatin are a hallmark of many diseases. We show here that a high fat (HF) diet leads to substantial chromatin remodeling in the livers of C57B...
ORGANISM(S): Mus musculus 
2014-07-17 | E-GEOD-55581 | biostudies-arrayexpress
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