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GenomicsWhole-genome nucleosome mapping in meiotic diploid S. cerevisiae
We determined nucleosome positions throughout the genome in diploid S. cerevisiae undergoing early stages of synchronous meiosis. This study sought to assess if systematic reorganization of nucleosomes occurs during meiotic prophase at or near sites of DNA double strand break formation. Six samples ...
ORGANISM(S): Saccharomyces cerevisiae 
2011-03-07 | E-GEOD-26452 | biostudies-arrayexpress
UnknownTargeting BRCA1 and BRCA2 Deficiencies with G-Quadruplex-Interacting Compounds.
Not available
S-EPMC4747901 | biostudies-literature
UnknownRandomized Phase II Trial of Gemcitabine Plus TH-302 Versus Gemcitabine in Patients With Advanced Pancreatic Cancer.
Not available
S-EPMC4881365 | biostudies-literature
UnknownAn Analysis of JADE2 in Non-Small Cell Lung Cancer (NSCLC).
Not available
S-EPMC10526426 | biostudies-literature
ProteomicsMCU activity compensates for Complex I dysfunction
Co-immunoprecipitation experiments were performed in HEK293T cells in the absence and presence of Flag-tagged MCU and binding proteins were identified by tandem mass spectrometry.
ORGANISM(S): Homo sapiens (Human) 
2022-03-10 | PXD018742 | Pride
Mitochondria Label-free Heart Co-ip Lc-ms/ms 
UnknownThe Effectiveness of Behavioral Interventions in Adults with Post-Traumatic Stress Disorder during Clinical Rehabilitation: A Rapid Review.
Not available
S-EPMC9224304 | biostudies-literature
ProteomicsEFHD1 promotes hepatocyte injury in metabolic liver disease by triggering Ca2+-dependent mitochondrial fission
Human genome-wide association studies (GWAS) of metabolic-associated steatohepatitis (MASH), the most common liver disease worldwide, have examined either liver injury biomarkers or liver fat content, with lipid metabolism enzymes ranked highly in both analyses. Here, to define pathophysiological pa...
ORGANISM(S): Mus musculus (Mouse) 
2026-07-30 | PXD069152 | Pride
Mouse Efhd1 Liver Mash 
TranscriptomicsGenome-wide discovery of human splicing branchpoints [BPCapture]
Gene splicing requires three basal genetic elements; the 3M-bM-^@M-^Y and 5M-bM-^@M-^Y splice sites and the branchpoint to which the 5M-bM-^@M-^Y intron termini is ligated to form a closed lariat during the splicing reaction. The 5M-bM-^@M-^Y and 3M-bM-^@M-^Y splice sites that define exon boundaries...
ORGANISM(S): Homo sapiens 
2014-10-01 | E-GEOD-53326 | biostudies-arrayexpress
ProteomicsProteomic profiling of serum in patients with pancreatic cystic lesions identifies novel biomarkers of pancreatic cancer risk
Pancreatic Cancer (PC) has the worst 5-year survival rate of any cancer as of 2024, at just 13%. The late-stage diagnosis of these patients limits their treatment options, further compounding the problem. Early detection of PC, therefore, is the primary concern of most PC research, as it has the pot...
ORGANISM(S): Homo sapiens (Human) 
2025-01-06 | PXD057661 | Pride
Human Pancreatic Serum Lc-ms Risk Pancreatic cancer Cystic lesions Proteomics Biomarkers 
ProteomicsHigh-Throughput Single Cell Proteomics Enabled by Multiplex Isobaric Labeling in a Nanodroplet Sample Preparation Platform
Single cell proteomics data from three murine cell lines (Raw, SVEC4-10, C10) and HeLa cell lysate. Samples were digested with trypsin and labeled with TMT 10-Plex on a small scale using nanoPOTS, followed by LC-MS/MS analysis.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Mus Musculus (ncbitaxon:10090) 
2019-07-19 | MSV000084110 | MassIVE
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