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GenomicsEFHD1 causes metabolic liver injury by triggering Ca2+-dependent mitochondrial fission
EFHD1 causes metabolic liver injury by triggering Ca2+-dependent mitochondrial fission
PRJNA1287721 | ENA
ProteomicsEFHD1 promotes hepatocyte injury in metabolic liver disease by triggering Ca2+-dependent mitochondrial fission
Human genome-wide association studies (GWAS) of metabolic-associated steatohepatitis (MASH), the most common liver disease worldwide, have examined either liver injury biomarkers or liver fat content, with lipid metabolism enzymes ranked highly in both analyses. Here, to define pathophysiological pa...
ORGANISM(S): Mus musculus (Mouse) 
2026-07-30 | PXD069152 | Pride
Mouse Efhd1 Liver Mash 
TranscriptomicsEFHD1 causes metabolic liver injury by triggering Ca2+-dependent mitochondrial fission
The occurrence of metabolic liver disease is increasing globally. Multiple GWAS studies have found an association between elevated EFHD1 expression in the liver and markers for metabolic liver disease in diverse populations. EFHD1 is a calcium-sensing protein at the mitochondrial outer membrane and ...
ORGANISM(S): Mus musculus 
2026-07-31 | GSE301924 | GEO
UnknownRegulation of axonal morphogenesis by the mitochondrial protein Efhd1.
Not available
S-EPMC7232985 | biostudies-literature
UnknownEFHD1, a novel mitochondrial regulator of tumor metastasis in clear cell renal cell carcinoma.
Not available
S-EPMC10154798 | biostudies-literature
UnknownEFHD1 ablation inhibits cardiac mitoflash activation and protects cardiomyocytes from ischemia.
Not available
S-EPMC9107497 | biostudies-literature
UnknownStructural and Biochemical Characterization of EFhd1/Swiprosin-2, an Actin-Binding Protein in Mitochondria.
Not available
S-EPMC7848108 | biostudies-literature
UnknownStructural and biochemical insights into Zn2+-bound EF-hand proteins, EFhd1 and EFhd2.
Not available
S-EPMC9980392 | biostudies-literature
UnknownFraternal twins: Swiprosin-1/EFhd2 and Swiprosin-2/EFhd1, two homologous EF-hand containing calcium binding adaptor proteins with distinct functions.
Not available
S-EPMC3036668 | biostudies-literature
UnknownThe Function of <i>Efhd1</i> <sup>+</sup> Telocytes in the Synovial Lymphatic System and Inflammatory-Erosive Arthritis.
Not available
S-EPMC12637515 | biostudies-literature
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