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TranscriptomicsExpression regulation by RYBP in mouse embryonic stem cells
Polycomb repressive complexes (PRCs) are important chromatin regulators of ES cell function. RYBP binds Polycomb H2A monoubiquitin ligases Ring1A and Ring1B, and has been suggested to participate in localizing Polycomb complexes to their targets. Moreover, constitutive inactivation of RYBP precludes...
ORGANISM(S): Mus musculus 
2012-04-03 | E-GEOD-32294 | biostudies-arrayexpress
TranscriptomicsExpression data from wild-type and Rybp-deficient ES cells
We used microarrays to investigate a global change in gene expression by conditional depletion of Rybp in mouse ES cells. Total RNAs were extracted from wild-type and Rybp-deficient ES cells, and were subjected to microarray analysis using Affymetrix GeneChip Mouse Genome 430A 2.0 arrays
ORGANISM(S): Mus musculus 
2012-04-03 | E-GEOD-32287 | biostudies-arrayexpress
TranscriptomicsRybp ChIP-chip in mouse ES cells
Rybp binding in wild-type, Eed-KO, and Dnmt1-KO ES cells ChIP on chip analysis was carried out using the Mouse Promoter ChIP-on-chip Microarray Set (G4490A, Agilent-014716 and Agilent-014717, Palo Alto, Calif., USA). ESCs were subjected to ChIP assay using a Rybp antibody (Santa Cruz; H-115). Purifi...
ORGANISM(S): Mus musculus 
2012-04-03 | E-GEOD-32289 | biostudies-arrayexpress
TranscriptomicsGene expression profile in Yaf2 KD and/or RYBP KO ES cells.
Gene expression change by Yaf2 KD in wild type or RYBP KO ES cells. Total RNAs were extracted from the respective ES cells, and were subjected to microarray analysis using Affymetrix GeneChip Mouse Genome 430A 2.0 arrays
ORGANISM(S): Mus musculus 
2012-04-03 | E-GEOD-32288 | biostudies-arrayexpress
ProteomicsElucidation of BMI1, RYBP and H2AK119ub interactomes in Glioblastoma
Identification of BMI1, RYBP and H2AK119UB interactome in Glioblastoma (GBM) to elucidate BMI1 roles independent of the PRC1-complex in GBM.
ORGANISM(S): Homo sapiens (Human) 
2021-09-09 | PXD022057 | Pride
H2ak119ub Bmi1 Proteomics Glioblastoma Ipms Chipms Rybp Gbm Lc-ms/ms 
GenomicsPCGF Homologs and RYBP Define Functionally Distinct PRC1 Family Complexes
The heterogeneous nature of mammalian PRC1 complexes has hindered our understanding of their biological functions. Here, we present a comprehensive proteomic and genomic analysis that uncovered six major groups of PRC1 complexes each containing a distinct PCGF subunit, a RING1A/B ubiquitin ligase, a...
ORGANISM(S): Homo sapiens 
2012-02-09 | E-GEOD-34774 | biostudies-arrayexpress
GenomicsPolycomb protein RYBP facilitates super-enhancer activity
Polycomb protein RYBP facilitates super-enhancer activity
PRJNA1183812 | ENA
GenomicsLack of Rybp in Mouse Embryonic Stem Cells Impairs Cardiac Differentiation
Lack of Rybp in Mouse Embryonic Stem Cells Impairs Cardiac Differentiation
PRJNA635578 | ENA
UnknownPolycomb protein RYBP facilitates super-enhancer activity.
Not available
S-EPMC11603947 | biostudies-literature
UnknownRYBP stabilizes p53 by modulating MDM2.
Not available
S-EPMC2637313 | biostudies-literature
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