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MetabolomicsThe Impacts of Sortase A and the 4'-Phosphopantetheinyl Transferase Homolog Sfp on Streptococcus mutans Extracellular Membrane Vesicle Biogenesis

Extracellular membrane vesicles (EMVs) are produced by many Gram-positive organisms, but information regarding vesiculogenesis is incomplete. We used single gene deletions to evaluate the impacts on Streptococcus mutans EMV biogenesis of Sortase A (SrtA), which affects S. mutans...

2021-10-06 | MTBLS1812 | MetaboLights
ProteomicsSite-specific mapping and quantification of protein S-sulphenylation in cells

Jing Yang, Vinayak Gupta, Kate S. Carroll, & Daniel C. Liebler, (2014) Nature Communications 5, 4776, doi:10.1038/ncomms5776

Cysteine S-sulphenylation provides redox regulation of protein f...

ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-08-28 | MSV000084244 | MassIVE
ProteomicsYang: Site-specific mapping and quantification of protein S-sulfenylation in cells
The files in this archive represent the supporting data for "Site-specific mapping and quantification of protein S-sulfenylation in cells," a paper to appear in Nature Communications (2014). The authors are Jing Yang, Vinayak Gupta, Kate S. Carroll, and Daniel C. Liebler, working at Vanderbilt Univ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2014-07-10 | MSV000078777 | MassIVE
TranscriptomicsThe unfolded protein response in fission yeast modulates stability of select mRNAs to maintain protein homeostasis
Homeostatic control mechanisms are essentil to life. One such mechanism, the unfolded protein response (UPR) operates in all eukarytic cells to adjust protein folding capacity of the endoplasmic reticulum (ER) according to need. UPR induction in all eurkarytic cells to date involves Ire1 (kinase/end...
ORGANISM(S): Schizosaccharomyces pombe 
2012-11-21 | E-GEOD-40298 | biostudies-arrayexpress
TranscriptomicsRNA-seq analysis of C. elegans CPEB homolog mutants.
Comparative transcriptomics study between C. elegans wild-type N2 and CPEB homolog mutants: fog-1, cpb-2, and cpb-3.
ORGANISM(S): Caenorhabditis elegans 
2017-08-03 | E-MTAB-4720 | biostudies-arrayexpress
ProteomicsIn vitro phosphorylation of ASY1 by CDKA;1
Meiosis is a complex cell division program reducing chromosome number as a prerequisite for sexual reproduction and at the same time leading to a new combination of parental alleles contributing to biodiversity. Little is known about how the distinct order of the molecular processes of meiosis are o...
ORGANISM(S): Arabidopsis Thaliana 
2019-10-01 | PXD011335 | panorama
ProteomicsThe C. elegans ASPP homolog APE-1 is a junctional Protein Phosphatase 1 modulator
Protein samples were analyzed by Multidimensional Protein Identification Technology (MudPIT), as described previously. Briefly, precipitated proteins were resuspended in 30uL of 100mM Tris pH 8.5 with 8M urea to denature proteins. Cysteines were reduced and alkylated prior to digestion with recombi...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Caenorhabditis Elegans (ncbitaxon:6239) 
2022-02-04 | MSV000088781 | MassIVE
TranscriptomicsThe conserved ubiquitin-like protein Hub1 plays a critical role in splicing in human cells
Different from canonical ubiquitin-like proteins, Hub1 does not form covalent conjugates with substrates but binds proteins non-covalently. In Saccharomyces cerevisiae, Hub1 associates with spliceosomes and mediates alternative splicing of SRC1, without affecting pre-mRNA splicing generally. Human H...
ORGANISM(S): Homo sapiens 
2014-05-30 | E-GEOD-56878 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of yeast mutants Gal-YAH1, Gal-ATM1 and Gal-NBP35 to investigate responses to defects in cellular Fe-S protein maturation
The biogenesis of iron-sulfur proteins in eukaryotes is an essential process involving the mitochondrial iron-sulfur cluster (ISC) assembly and export machineries and the cytosolic Fe/S protein assembly (CIA) apparatus. To define the integration of Fe/S protein biogenesis into cellular homeostasis, ...
ORGANISM(S): Saccharomyces cerevisiae 
2007-12-14 | E-MEXP-1215 | biostudies-arrayexpress
TranscriptomicsAn SRY homolog cooperates with a transposon-derived CENP-B protein to control sex-specific directed recombination
Occupancy profiling of Myc tagged Mc protein in fission yeast. Agilent 60mer array was used to analyze DNA recovered by immunoprecipitation of Mc-myc protein from culture of fission yeast.
ORGANISM(S): Schizosaccharomyces pombe 
2011-11-21 | E-GEOD-32996 | biostudies-arrayexpress
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