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Our studies reveal that S100A16 overexpression triggers GC cells proliferation and migration both in vivo and in vitro; by contrast, S100A16 knockdown restricts the speed of GC cells growth and mobility. Proteomic analysis results reveal a large S100A16 interactome, which includes ZO-2 (Zonula Occlu...
ORGANISM(S): Homo sapiens (Human) 
2022-02-17 | PXD028022 | Pride
Effect of depletion of S100A16 on gene expression during lipid accumulation of primary hepatocytes
S100a16 deficiency prevents liver fibrosis via inhibiting C-X-C motif chemokine receptor 4 expression
mRNA-seq analysis of S100A16-mediated alternative splicing in lung adenocarcinoma under oxidative stress
Identification and Functional Analysis of MYEOV, KCNN4, S100A16 and DDX60L in Pancreatic Ductal Adenocarcinoma
Liver fibrosis has been implicated in the pathogenesis of various liver disease. Thus far, there is still no effective intervention means for this process. Recently, we have demonstrated that S100A16 participated in liver lipid accumulation and renal fibrosis. Therefore, we hypothesized that S100A16...
ORGANISM(S): Mus musculus 
2022-03-25 | GSE199294 | GEO
Alcoholic liver disease (ALD) encompasses conditions ranging from simple steatosis to cirrhosis and even liver cancer. It has gained significant global attention in recent years. Despite this, effective pharmacological treatments for ALD remain elusive, and the core mechanisms underlying the disease...
ORGANISM(S): Mus musculus 
2023-09-26 | GSE243683 | GEO
Lung adenocarcinoma (LUAD) cells develop adaptive mechanisms to survive high oxidative stress in the tumor microenvironment. This study aims to elucidate the role of S100A16, a calcium-binding protein, in regulating mitochondrial quality control and oxidative stress resistance. We performed polyA-en...
ORGANISM(S): Homo sapiens 
2026-08-06 | GSE330179 | GEO
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