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UnknownBasal complex: a smart wing component for automatic shape morphing.
Not available
S-EPMC10435446 | biostudies-literature
UnknownAn insect-inspired asymmetric hinge in a double-layer membrane.
Not available
S-EPMC9661187 | biostudies-literature
ProteomicsHigh-Content Screening Identifies A Small Molecule That Restores AP-4-dependent Protein Trafficking In Neuronal Models Of AP-4-Associated Hereditary Spastic Paraplegia
Unbiased phenotypic screens in patient-relevant disease models offer the potential to detect therapeutic targets for rare diseases. In this study, we developed a high-throughput screening assay to identify molecules that correct aberrant protein trafficking in adaptor protein complex 4 (AP-4) defici...
ORGANISM(S): Homo sapiens (Human) 
2024-01-26 | PXD042950 | Pride
Human Autophagy Ipsc Drug screen Protein trafficking Hsp 
UnknownNanoformulated 3'-diindolylmethane modulates apoptosis, migration, and angiogenesis in breast cancer cells.
Not available
S-EPMC10770460 | biostudies-literature
UnknownSARS-CoV-2 Infection of Human Neurons Is TMPRSS2 Independent, Requires Endosomal Cell Entry, and Can Be Blocked by Inhibitors of Host Phosphoinositol-5 Kinase.
Not available
S-EPMC10134833 | biostudies-literature
UnknownSARS-CoV-2 infection in hiPSC-derived neurons is cathepsin-dependent and causes differential accumulation of HIF1ɑ and phosphorylated tau.
Not available
S-EPMC12597281 | biostudies-literature
UnknownUtility of targeted gene sequencing to differentiate myeloid malignancies from other cytopenic conditions.
Not available
S-EPMC10368770 | biostudies-literature
ProteomicsDDHD2 interacts with STXBP1 to mediate long-term memory via the generation of saturated free fatty acidsDDHD2 interacts with STXBP1 to mediate long-term memory via the generation of saturated free fatty acids
The phospholipid and free fatty acid (FFA) composition of neuronal membranes plays a crucial role in learning and memory, but the mechanisms through which neuronal activity affects the brain's lipid landscape remain largely unexplored. Saturated FFAs, particularly myristic acid (C14:0), strongly inc...
ORGANISM(S): Rattus norvegicus (Rat) 
2024-05-22 | PXD047812 | Pride
Phospholipase a1  free fatty acids  myristic acid  learning and memory Lipids 
UnknownDDHD2 provides a flux of saturated fatty acids for neuronal energy and function.
Not available
S-EPMC12552131 | biostudies-literature
UnknownEpidemiology and outcomes of hospital-acquired bloodstream infections in intensive care unit patients: the EUROBACT-2 international cohort study.
Not available
S-EPMC9916499 | biostudies-literature
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