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TranscriptomicsTranscriptional profiling of ATCC46645 strain and isogenic M-NM-^TpacC Aspergillus fumigatus mutant during murine infection
In lung diseases caused by the major mould pathogen Aspergillus fumigatus the pulmonary epithelium is destroyed by invasive growth of fungal hyphae, a process thought to require fungal proteases. Here we show that the A. fumigatus pH-responsive transcription factor PacC governs expression of secrete...
ORGANISM(S): Aspergillus fumigatus 
2014-10-20 | E-GEOD-54810 | biostudies-arrayexpress
UnknownMolecular Screening of Carbapenem-Resistant K. pneumoniae (CRKP) Clinical Isolates for Concomitant Occurrence of Beta-Lactam Genes (CTX-M, TEM, and SHV) in the Kingdom of Bahrain.
Not available
S-EPMC10744081 | biostudies-literature
TranscriptomicsStudy of poplar shoot apex transcriptomic response to variations in soil water avaialbility
In a context of climate changes, water availability is expected to become a limiting factor for plant growth and to have an impact on forest health. In order to identify genes involved in shoot phenotypic plasticity in response to variations in water availability in trees, gene expression patterns w...
ORGANISM(S): Populus x canadensis 
2014-01-01 | E-GEOD-46605 | biostudies-arrayexpress
UnknownReceptor-Based Pharmacophore Modeling in the Search for Natural Products for COVID-19 Mpro.
Not available
S-EPMC8000608 | biostudies-literature
GenomicsCandida albicans induces monocyte training via epigenetic programming through a dectin 1-dependent pathway
Non-specific protective effects against reinfection have been described following infection with Candida albicans. Here we show that mice defective in functional T and B lymphocytes were protected against reinfection with C. albicans in a monocyte-dependent manner. C. albicans and beta glucans induc...
ORGANISM(S): Homo sapiens 
2012-12-21 | E-GEOD-34260 | biostudies-arrayexpress
TranscriptomicsThe Mitochondrial Calcium Uniporter controls skeletal muscle mass in vivo
Muscle atrophy contributes to the poor prognosis of many physiopathological conditions, but pharmacological therapies are still limited. Muscle activity leads to major swings in mitochondrial [Ca2+] which control aerobic metabolism, cell death and survival pathways. We have investigated in vivo the ...
ORGANISM(S): Mus musculus 
2015-03-05 | E-GEOD-60931 | biostudies-arrayexpress
UnknownInvestigation of Newly Synthesized Bis-Acyl-Thiourea Derivatives of 4-Nitrobenzene-1,2-Diamine for Their DNA Binding, Urease Inhibition, and Anti-Brain-Tumor Activities.
Not available
S-EPMC10051851 | biostudies-literature
TranscriptomicsGene expression profiling of human peripheral blood lymphocytes cultured in modeled microgravity
In the present study we analyzed miRNA and mRNA expression profiles in human peripheral blood lymphocytes (PBLs) incubated in microgravity condition, simulated by a ground-based Rotating Wall Vessel (RWV) bioreactor. Our results show that 42 miRNAs were differentially expressed in MMG-incubated PBLs...
ORGANISM(S): Homo sapiens 
2014-07-17 | E-GEOD-57408 | biostudies-arrayexpress
TranscriptomicsHigh IGFBP2 Expression Correlates with Tumor Severity in Pediatric Rhabdomyosarcoma.
Rhabdomyosarcoma (RMS) is the most common childhood sarcoma and is identified as either the embryonal or alveolar (ARMS) subtype. In approximately 75% of cases, ARMSs are characterized by specific chromosomal translocations that involve PAX and FKHR genes. ARMS gene expression signatures vary, depen...
ORGANISM(S): Homo sapiens 
2011-12-05 | E-GEOD-23196 | biostudies-arrayexpress
UnknownSpheriCal® -ESI: A dendrimer-based nine-point calibration solution ranging from m/z 273 to 1716 for electrospray ionization mass spectrometry peptide analysis.
Not available
S-EPMC7900979 | biostudies-literature
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