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ModelsMacNamara2012 - Signal transduction
MacNamara2012 - Signal transduction A toy model of signal tranduction to illustrate how different logic formalizms (Boolean, fuzzy logic and differential equations) treat state and time, is described here. This model was generated from the PKN-ToyPB.sif file available in...
2005-01-01 | MODEL1305240000 | BioModels
ProteomicsThe ubiquitin ligase UBR5 suppresses proteostasis collapse in immortal pluripotent stem cells and Huntington’s disease models
Pluripotent stem cells undergo unlimited self-renewal while maintaining their potential to differentiate into post-mitotic cells with an intact proteome, a capacity that demands a highly induced proteostasis network. As such, induced pluripotent stem cells (iPSCs) suppress the aggregation of polyQ-e...
ORGANISM(S): Homo sapiens (Human) 
2018-06-14 | PXD009803 | Pride
Human cells (293) Htt 
ProteomicsSomatic increase of CCT8 mimics proteostasis of human pluripotent stem cells and extends C. elegans lifespan
Human embryonic stem cells can replicate indefinitely while maintaining their undifferentiated state and, therefore, are immortal in culture. This capacity may demand avoidance of any imbalance in protein homeostasis (proteostasis) that would otherwise compromise stem cell identity. Here we show tha...
ORGANISM(S): Homo sapiens (Human) 
2017-03-23 | PXD005123 | Pride
Neurons Chaperome Embryonic stem cells Neural progenitors cells 
UnknownPhosphorylation of S6RP in peritubular capillaries of kidney grafts and circulating HLA donor-specific antibodies.
Not available
S-EPMC9622791 | biostudies-literature
UnknownDendritic Cells from HIV Controllers Have Low Susceptibility to HIV-1 Infection In Vitro but High Capacity to Capture HIV-1 Particles.
Not available
S-EPMC4978443 | biostudies-literature
UnknownMitochondrial DNA and TLR9 drive muscle inflammation upon Opa1 deficiency.
Not available
S-EPMC5978453 | biostudies-literature
UnknownEarly antiretroviral therapy favors post-treatment SIV control associated with the expansion of enhanced memory CD8<sup>+</sup> T-cells.
Not available
S-EPMC10784587 | biostudies-literature
UnknownThe mycotoxin phomoxanthone A disturbs the form and function of the inner mitochondrial membrane.
Not available
S-EPMC5833434 | biostudies-literature
UnknownInternational Changes in COVID-19 Clinical Trajectories Across 315 Hospitals and 6 Countries: Retrospective Cohort Study.
Not available
S-EPMC8510151 | biostudies-literature
ProteomicsThe Global Phosphorylation Landscape of SARS-CoV-2 Infection
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of the coronavirus disease 2019 (COVID-19) pandemic, has infected over 3 million people worldwide and caused over 200,000 deaths since it emerged in late 2019. There is an urgent need to develop therapies that can limi...
ORGANISM(S): Chlorocebus Aethiops (ncbitaxon:9534) 
2020-07-15 | MSV000085759 | MassIVE
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