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TranscriptomicsNickel Chloride (NiCl2) effect on human T cells from whole blood
Analysis of anti-CD3/anti-CD28 stimulated T cells treated with or without nickel chloride. Nickel is the most important contact allergen in the general population of the industrialized world. Results provide insight into the biological effects of nickel on human CD3+ T cells. We obtained mRNA of pur...
ORGANISM(S): Homo sapiens 
2011-05-18 | E-GEOD-23387 | biostudies-arrayexpress
TranscriptomicsA mutation of RNA polymerase β’ subunit (RpoC) converts heterogeneously vancomycin-intermediate S. aureus (hVISA) into ‘slow-VISA’ (sVISA)
Various mutations in the rpoB gene, which encodes the RNA polymerase beta subunit, are associated with increased vancomycin (VAN) resistance in vancomycin-intermediate S. aureus (VISA) and hetero-VISA (hVISA) strains. We reported that rpoB mutations are also linked to the expression of the recently ...
ORGANISM(S): Staphylococcus aureus 
2015-05-08 | E-GEOD-65338 | biostudies-arrayexpress
TranscriptomicsSeeking genes responsible for developmental origins of health and disease from the fetal mouse liver in food restricted model
Non-optimal fetal environments resulting in low birth weight have epidemiologically been associated with adult diseases. In animal models, maternal undernutrition has successfully demonstrated increased risks for adult diseases. In the present study, we treated pregnant mice with 50% food restrictio...
ORGANISM(S): Mus musculus 
2013-08-20 | E-GEOD-49964 | biostudies-arrayexpress
TranscriptomicsA DNA Microarray Analysis of Rat Intestine, Spleen and Liver Transcriptome after Oral Administration of Lavender Oil
Lavender oil (LO) – a commonly used oil in aromatherapy with well defined volatile components linalool and linalyl acetate – use in non-traditional medicine is increasing globally. To understand and provide evidence for the potential positive effects of LO on the body, we have established an animal ...
ORGANISM(S): Rattus norvegicus 
2014-11-26 | E-GEOD-63640 | biostudies-arrayexpress
TranscriptomicsSeeking genes responsible for developmental origins of health and disease from the fetal mouse liver following maternal food restriction [Methylation]
Non-optimal fetal environments resulting in low birth weight have epidemiologically been associated with a higher risk of adult diseases. In animal models, maternal undernutrition has successfully demonstrated that offspring owed increased risks for adult diseases. In mice, shorten life span was als...
ORGANISM(S): Mus musculus 
2013-11-19 | E-GEOD-52517 | biostudies-arrayexpress
TranscriptomicsUnraveling the Rat Blood Genome-Wide Transcriptome after the Oral Administration of Lavender Oil by a Two-Color Dye-Swap DNA Microarray Approach
Lavender oil (LO) is commonly used oil in aromatherapy, with well-defined volatile components linalool and linalyl acetate, in non-traditional medicine. To understand and demonstrate the potential positive effects of LO on the body, we have established an animal model for investigating the orally ad...
ORGANISM(S): Rattus norvegicus 
2015-04-02 | E-GEOD-67499 | biostudies-arrayexpress
TranscriptomicsComparative global gene expression profiling of mice liver and spleen fed with nucleoprotein (NP) diets
A diet rich in nucleic acids and protamin protein, termed as nucleoprotein was used for the study. Mice were fed with NP diets for 4 weeks followed by removal of the liver and spleen. Total RNA extracted from livers and spleens was pooled in each group (low NP or LNP-control, and 1.2% NP-treatment, ...
ORGANISM(S): Mus musculus 
2011-04-13 | E-GEOD-28505 | biostudies-arrayexpress
TranscriptomicsAlteration of gene expression patterns in the liver and spleen following exposure to nucleoprotein diet in the mouse LPS injection model
A diet rich in nucleic acids and protamin protein, termed as nucleoprotein (NP), has been attracting a great deal of attention in food science for its beneficial effects. In the present study, we performed a global gene expression profiling in mice fed with NP diet rich in nucleoproteins from the sa...
ORGANISM(S): Mus musculus 
2011-04-01 | E-GEOD-28176 | biostudies-arrayexpress
TranscriptomicsSeeking genes responsible for developmental origins of health and disease (DOHaD) from the fetal mouse brain following maternal food deprivation (FD) and food restriction (FR) using OMICS approach
A non-optimal fetal environment is known to cause low birth weight, which has been epidemiologically associated with a greater risk of adult diseases. Maternal undernutrition in animal models has also revealed the increased risks for adult diseases in the offspring. In this study, pregnant mice unde...
ORGANISM(S): Mus musculus 
2015-09-19 | E-GEOD-73202 | biostudies-arrayexpress
TranscriptomicsSeeking Gene Candidates Responsible for Developmental Origins of Health and Disease (DOHaD)
Human epidemiological evidence has led scientists to theorize that undernutrition during gestation is an important early origin of adult diseases. Animal models have successfully demonstrated that maternal diet could contribute to some of adult diseases. Undernutrition is perceived harmful in pregna...
ORGANISM(S): Mus musculus 
2011-04-01 | E-GEOD-28175 | biostudies-arrayexpress
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