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ModelsFanconi anemia and checkpoint recovery
The FA/BRCA pathway repairs DNA interstrand crosslinks. Mutations in this pathway cause Fanconi anemia (FA), a chromosome instability syndrome with bone marrow failure and cancer predisposition. Upon DNA damage, normal and FA cells inhibit the cell cycle progression, until the G2/M checkpoint is tur...
4790 | Cell Collective
ProteomicsPeptide sequences generated by unexpected splicing
Transcripts from the human and mouse CAPN10 cDNA sequences cloned into pcDNA and expressed in cultured cells undergo unexpected splicing. Peptide sequences missing from the spliced version of CAPN10 expressed in COS7 cells were determined by MS analysis.
ORGANISM(S): Homo Sapiens (human) Mus Musculus (mouse) 
2022-01-01 | PXD026551 | JPOST Repository
ProteomicsProteomics for identification of CAPN10 targets
Protease activity dependent proteome change of COS7 cells expressing CAPN10a or CAPN10c was analyzed using iTRAQ reagents. iTRAQ114 and 116 for WT, iTRAQ115 and 117 for C73S mutant.
ORGANISM(S): Cellular Organisms 
2022-01-01 | PXD026552 | JPOST Repository
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