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ProteomicsRIME against PBX1 protein in P19.6 mouse embryonal carcinoma cells treated for 48 hours with all-trans retinoic acid
Identification of PBX1 interactors in P19.6 mouse embryonal carcinoma cells treated for 48 hours with all-trans retinoic acid.
ORGANISM(S): Mus musculus (Mouse) 
2017-04-03 | PXD006158 | Pride
Pbx1 
TranscriptomicsCell cycle-dependent reconfiguration of the DNA (hydroxy) methylome during terminal differentiation of human B cells into plasma cells
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2015-10-30 | E-GEOD-72498 | biostudies-arrayexpress
GenomicsGenome-wide mapping of 5-hydroxymethylcytosine (5hmC) during differentiation of P19.6 and 3T3-L1 cells
Enhancers are developmentally-controlled transcriptional regulatory regions whose activities are modulated through histone modifications or histone variant deposition. Here, we show by genome-wide mapping that the newly discovered DNA modification 5-hydroxymethylcytosine (5hmC) is dynamically associ...
ORGANISM(S): Mus musculus 
2012-06-04 | E-GEOD-38407 | biostudies-arrayexpress
GenomicsGenome-wide analysis of Estrogen Receptor-mediated response to acute Estradiol treatment in liver (ChIP-seq)
Estrogen-based treatments have numerous extra-reproductive effects. On the one hand, they have protective metabolic actions against abdominal fat accumulation, type 2 diabetes, liver steatosis,… But, on the other hand, the oral route of administration, presumably due to a hepatic impact on liver-d...
ORGANISM(S): Mus musculus 
2016-05-13 | E-GEOD-70346 | biostudies-arrayexpress
GenomicsMapping of 5-hydroxymethylcytosine by selective chemical labeling (SCL-seq) in human naive B cells and in vitro differentiated plasmablasts (P1 cells) [HTS]
We report the genome-wide mapping of 5hmC in naive B cells and in vitro differentiated plasmablasts (P1 cells). In addition, H3K4me1 and H3K27ac histne marks were mapped in in vitro differentiated plasmablasts from two healthy donors (BN358 and BN369) by ChIP-seq. Genomic DNA from human primary cell...
ORGANISM(S): Homo sapiens 
2015-10-30 | E-GEOD-72360 | biostudies-arrayexpress
TranscriptomicsGenome-wide analysis of Estrogen Receptor-mediated response to acute Estradiol treatment in liver (expression)
Estrogen-based treatments have numerous extra-reproductive effects. On the one hand, they have protective metabolic actions against abdominal fat accumulation, type 2 diabetes, liver steatosis,… But, on the other hand, the oral route of administration, presumably due to a hepatic impact on liver-d...
ORGANISM(S): Mus musculus 
2016-05-13 | E-GEOD-70329 | biostudies-arrayexpress
TranscriptomicsCell-specific and spatio-temporal controls of the estrogen-responsive trefoil factor (TFF) locus activity
Cell-specific transcriptional regulations exerted by the estrogen (E2) receptor alpha (ER) heavily rely upon timely and spatially coordinated processes. We engaged a comparative analysis of such dynamic molecular events at the TFF locus harbouring a cluster of genes co-regulated by E2, in two distin...
ORGANISM(S): Homo sapiens 
2014-05-06 | E-GEOD-32132 | biostudies-arrayexpress
TranscriptomicsCell-specific and spatio-temporal controls of the estrogen-responsive trefoil factor (TFF) locus activity.II.
Cell-specific transcriptional regulations exerted by the estrogen (E2) receptor alpha (ER) heavily rely upon timely and spatially coordinated processes. We engaged a comparative analysis of such dynamic molecular events at the TFF locus harbouring a cluster of genes co-regulated by E2, in two distin...
ORGANISM(S): Homo sapiens 
2014-05-06 | E-GEOD-23850 | biostudies-arrayexpress
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