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TranscriptomicsProfile the RNA composition of cell-free saliva and salivary exosomes
We compared the transcriptomic content of salivary exosomes vs. whole saliva via microarray (Affymetrix HU133 plus 2.0). Unstimulated saliva samples and derived exosome-like microvesicles were obtained from 3 healthy volunteers and processed for RNA isolation and microarray analysis.
ORGANISM(S): Homo sapiens 
2014-09-10 | E-GEOD-50700 | biostudies-arrayexpress
TranscriptomicsDetermination of transcriptome of SptR in group A Streptococcus during growth in human saliva
The molecular genetic mechanisms used by bacteria to persist in humans are poorly understood. Group A Streptococcus (GAS) causes the majority of bacterial pharyngitis cases in humans and is prone to persistently inhabit the upper respiratory tract. To gain information about how GAS survives in and i...
ORGANISM(S): Streptococcus sp. 'group A' 
2010-05-19 | E-GEOD-16124 | biostudies-arrayexpress
TranscriptomicsDevelopment of Transcriptomic Biomarker Signature in Human Saliva to Detect Lung Cancer
Affymetrix HG U133 Plus 2.0 Array (Affymetrix, Santa Clara, CA) was used to profile transcriptomes and discover altered gene expression in saliva supernatant. Salivary transcriptomic biomarker discovery was performed on 10 lung cancer patients and 10 matched controls. Seven messenger RNA biomarkers ...
ORGANISM(S): Homo sapiens 
2013-01-11 | E-GEOD-32175 | biostudies-arrayexpress
TranscriptomicsEpigenome analysis of saliva samples from alcohol users
Genome wide DNA methylation profiling of saliva DNA from 197 alcohol dependent subjects. The Illumina Infinium 27k Human DNA methylation Beadchip v1.2 was used to obtain DNA methylation profiles across approximately 27,000 CpGs in saliva samples. Bisulphite converted DNA were hybridised to the Illum...
ORGANISM(S): Homo sapiens 
2011-12-01 | E-GEOD-34035 | biostudies-arrayexpress
TranscriptomicsArabidopsis thaliana gene expression changes upon treatment with green peach aphid saliva
Myzus persicae (green peach aphid) feeding on Arabidopsis thaliana induces a defense response, quantified as reduced aphid progeny production, in infested leaves but not in other parts of the plant. Similarly, infiltration of aphid saliva into Arabidopsis leaves causes only a local increase in aphid...
ORGANISM(S): Arabidopsis thaliana 
2009-06-23 | E-GEOD-16497 | biostudies-arrayexpress
TranscriptomicsPancreatic cancer biomarkers in mouse saliva
This is a pilot study. We are trying to detect potential salivary biomarkers in mice with a pancreatic tumor. Global gene expression profiling has shown great promise in high-throughput biomarker discovery for early disease detection in body fluids such as saliva, which is accessible, cost-effectiv...
ORGANISM(S): Mus musculus 
2013-06-12 | E-GEOD-47811 | biostudies-arrayexpress
ProteomicsEvaluation of suitability of dried saliva spots for in-depth proteome analyses of clinical applications
We performed a single-shot DIA-MS proteome analysis of dried saliva spots (DSS) to investigate whether it provides a platform to complement the dried blood spot (DBS) data.
ORGANISM(S): Homo Sapiens (human) 
2022-04-26 | PXD031181 | JPOST Repository
TranscriptomicsTranscription profiling of human saliva exosomes
Exosomes are molecular entities derived from membrane vesicles of endocytic origin secreted by most cell types. These vesicles are implicated in cell-to-cell communication, deliver proteins and mRNA molecules between cells. Recent studies have shown that exosomes are found in body fluids such as sal...
ORGANISM(S): Homo sapiens 
2008-11-15 | E-GEOD-13494 | biostudies-arrayexpress
ProteomicsEvaluation of suitability of dried saliva spots for in-depth proteome analyses of clinical applications - Additional file
We performed a single-shot DIA-MS proteome analysis of dried saliva spots (DSS) to investigate whether it provides a platform to complement the dried blood spot (DBS) data.
ORGANISM(S): Homo Sapiens (human) 
2022-04-26 | PXD032116 | JPOST Repository
TranscriptomicsTranscription profiling of human primary Sjogrens syndrome and control whole saliva samples
10 saliva samples from patients with primary Sojgren's syndrome and 10 saliva samples from control subjects Experiment Overall Design: Gene profilling from 10 saliva samples from patients with primary Sojgren's syndrome and 10 saliva samples from control subjects using Affymetrix HGu133+2 microarray...
ORGANISM(S): Homo sapiens 
2008-06-15 | E-GEOD-7451 | biostudies-arrayexpress
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