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TranscriptomicsSingle cell RNA-sequencing of epithelial cells, endothelial cells and macrophages from mouse submandibular salivary glands
The salivary glands often become damaged in individuals receiving radiotherapy for head and neck cancer, resulting in chronic dry mouth. This leads to detrimental effects on their health and quality of life, for which there is no regenerative therapy. Macrophages are the predominant immune cell in t...
ORGANISM(S): Mus musculus 
2023-10-01 | E-MTAB-13374 | biostudies-arrayexpress
ProteomicsFunctional Human Salivary Gland Organoids for Tissue Regeneration in Chemically Defined Culture Systems
Salivary gland dysfunction significantly impairs patients' quality of life, yet effective regenerative therapies remain clinically unavailable. In this study, we established a fully chemically defined, xeno-free three-dimensional culture system to generate functional human salivary gland organoids. ...
ORGANISM(S): Mus Musculus 
PXD066438 |
GenomicsCD9-Enriched Extracellular Vesicles from Salivary Gland Basal Progenitors to Promote Regeneration in Salivary Gland Fibrosis
CD9-Enriched Extracellular Vesicles from Salivary Gland Basal Progenitors to Promote Regeneration in Salivary Gland Fibrosis
PRJNA975515 | ENA
UnknownThe intact parasympathetic nerve promotes submandibular gland regeneration through ductal cell proliferation.
Not available
S-EPMC8249781 | biostudies-literature
UnknownSalivary gland progenitor cell biology provides a rationale for therapeutic salivary gland regeneration.
Not available
S-EPMC3375332 | biostudies-literature
ProteomicsQuantitative Analysis of Differential Proteomes in Mouse Mesenchymal Stem Cells Converted to Salivary Epithelial Precursors
Severe hyposalivation often results from Sjögren’s syndrome or radiation therapy for head and neck cancer. Devastating consequences of hyposalivation, such as rampant dental caries and persistent oral candidiasis, compromise the quality of life in those patients. Clinical management for dry mouth ty...
ORGANISM(S): Mus musculus (Mouse) 
2017-02-14 | PXD002796 | Pride
Proteomics Dry mouth Salivary epithelial precursors Co-culture Transcription factors Bone marrow-derived mesenchymal stem cells Itraq Salivary gland regeneration 
GenomicsCD9-Enriched Extracellular Vesicles from Salivary Gland Basal Progenitors to Promote Regeneration in Salivary Gland Fibrosis
Effect of miRNAs from CD9+ EVs in salivary gland epithelail cell for anti-fibrotic regeneration in obstructive sialadenitis.
ORGANISM(S): Homo sapiens 
2025-02-18 | GSE233238 | GEO
GenomicsGene expression of murine 3 major salivary gland organoids
Gene expression of murine 3 major salivary gland organoids
PRJNA763166 | ENA
UnknownL1 Peptide-Conjugated Fibrin Hydrogels Promote Salivary Gland Regeneration.
Not available
S-EPMC5480806 | biostudies-literature
UnknownStrategies for Developing Functional Secretory Epithelia from Porcine Salivary Gland Explant Outgrowth Culture Models.
Not available
S-EPMC6921070 | biostudies-literature
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