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Doxorubicin (DOX) is a widely used chemotherapeutic agent that can cause off-target gastrointestinal (GI) toxicity. This experiment profiles DOX-induced transcriptomic responses by RNA-seq in mouse colon tissue (in vivo) across dose and time. Mice received DOX at 5 or 10 mg/kg by intravenous bolus i...
ORGANISM(S): Mus musculus 
Doxorubicin (DOX) is a widely used chemotherapeutic agent that can cause off-target gastrointestinal (GI) toxicity. This experiment profiles DOX-induced transcriptomic responses by RNA-seq in mouse colonoids (in vitro) across dose and time. Mouse colonoids were sampled at 24, 48 and 72 h after expos...
ORGANISM(S): Mus musculus 
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