Salmon David P DP

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Gene expression profiling of resistant and susceptible Atlantic salmon fry challenged with Infectious Pancreatic Necrosis virus

Infectious Pancreatic Necrosis (IPN) is a highly contagious birnavirus disease of farmed salmonid fish, which often causes high levels of morbidity and mortality. A large genetic component underlying resistance to this disease has been previously described for Atlantic salmon (Salmo salar L.), which...

ORGANISM(S): Salmo salar

2016-04-07 | E-MTAB-4275 | biostudies-arrayexpress

IL-10 production and metabolic regulation in macrophages are linked by a TLR-driven CREB-mediated mechanism

IL-10 is produced by macrophages in diverse immune settings and is critical in limiting immune-mediated pathology. In helminth infections macrophages are an important source of IL-10, however the molecular mechanism underpinning production of IL-10 by these cells is poorly characterized. Here, bone ...

ORGANISM(S): Mus musculus

2015-07-08 | E-GEOD-64844 | biostudies-arrayexpress

A library of yeast transcription factor motifs

The sequence specificity of DNA-binding proteins is the primary mechanism by which the cell recognizes genomic features. Here, we describe systematic determination of yeast transcription factor DNA-binding specificities. We obtained binding specificities for 112 DNA-binding proteins representing 19 ...

ORGANISM(S): Saccharomyces cerevisiae

2008-12-26 | E-GEOD-12349 | biostudies-arrayexpress

Higher dose corticosteroids in hospitalised COVID-19 patients requiring ventilatory support (RECOVERY): a randomised, controlled, open-label, platform trial.

Not available

S-EPMC11872607 | biostudies-literature

Same data, different analysts: variation in effect sizes due to analytical decisions in ecology and evolutionary biology.

Not available

S-EPMC11804095 | biostudies-literature

Boosted lopinavir- versus boosted atazanavir-containing regimens and immunologic, virologic, and clinical outcomes: a prospective study of HIV-infected individuals in high-income countries.

Not available

S-EPMC4447777 | biostudies-literature

Metformin for patients with metastatic prostate cancer starting androgen deprivation therapy: a randomised phase 3 trial of the STAMPEDE platform protocol.