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MetabolomicsGut Microbial and Metabolic Responses to Salmonella enterica Serovar Typhimurium and Candida albicans

The gut microbiota is increasingly recognized for playing a critical role in human health and disease, especially in conferring resistance to both virulent pathogens such as Salmonella, which infects 1.2 million people in the United States every year [1], and opportunistic pathogens like Candida,...

2019-09-20 | MTBLS753 | MetaboLights
MetabolomicsCo-exposure to Polyethylene Fiber and Salmonella enterica Typhimurium Alters Microbiome and Metabolome of in vitro Chicken Cecal Mesocosms
Humans and animals encounter a summation of exposures during their lifetime (the exposome). In recent years, the scope of the exposome has begun to include microplastics. Microplastics (MPs) have increasingly been found in locations where there could be an interaction with Salmonella enterica Typhim...
2024-07-08 | MTBLS9001 | MetaboLights
MetabolomicsSalmonella enterica and Pseudomonas syringe uniquely alter the exometabolomic profile of the Arabidopsis leaf surface
To successfully colonize healthy plants, bacterial pathogens must overcome stressful conditions on the leaf surface before entering the leaf tissues through natural openings. In this study, we developed an approach to examine the exometabolomic profiles of the leaf surface when exposing plants with ...
2025-06-17 | MTBLS9884 | MetaboLights
MetabolomicsThe impact of slyA on cell metabolism of Salmonella Typhimurium: a joint study of transcriptomics and metabolomics

Salmonella Typhimurium (S. typhimurium), a gram-negative foodborne pathogen, is the leading cause of Salmonella food poisoning in humans. slyA has been demonstrated to be a critical transcriptional regulator in S. typhimurium, enabling the pathogen to survive in host cells by modulating the expre...

2020-10-11 | MTBLS1858 | MetaboLights
TranscriptomicsTranscription profiling of Salmonella enterica serovar Typhimurium definitive phage type 104 (DT104) isolates
Salmonella enterica serovar Typhimurium (S. Typhimurium) definitive phage type 104 (DT104) has caused significant morbidity and mortality in humans and animals for almost three decades. We have completed the full DNA sequence of one DT104 strain, NCTC13348 and show that the main differences between ...
ORGANISM(S): Salmonella enterica 
2008-09-05 | E-MTAB-20 | biostudies-arrayexpress
MetabolomicsIntegrated Metabolomics and Transcriptomics Suggest the Global Metabolic Response to 2-Aminoacrylate Stress in Salmonella enterica
Not available
ORGANISM(S): Salmonella enterica 
ST001305 | MetabolomicsWorkbench
MetabolomicsA pathogen-specific isotope tracing approach reveals metabolic activities and fluxes of intracellular Salmonella

Pathogenic bacteria proliferating inside mammalian host cells need to rapidly adapt to the intracellular environment. How they achieve this and scavenge essential nutrients from the host has been an open question due to the difficulties in distinguishing between bacterial and host metabolites

2023-08-02 | MTBLS1275 | MetaboLights
TranscriptomicsTranscription profiling of Salmonella enterica serovar Typhimurium hha ydgT mutants
transcriptomic analysis of hha ydgT mutants in Salmonella enterica serovar Typhimurium
ORGANISM(S): Salmonella typhimurium 
2008-01-01 | E-MEXP-1303 | biostudies-arrayexpress
no omics definedTranscription profiling of wild type, waaG mutant and rfaH mutant Salmonella enterica serovar Enteritidis PT4 and serovar Typhimurium to investigate live-attenuated vacine candidates
Effect of mutation of rfaH on gene expression in Salmonella enterica serovar Enteritidis PT4 and Salmonella enterica serovar Typhimurium 4/74
ORGANISM(S): Salmonella enterica 
2006-11-13 | E-MEXP-844 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Salmonella enterica serovar Typhimurium SL1344 and a SL1344 ramA gene knockout
The transcriptomes of Salmonella enterica serovar Typhimurium SL1344 and SL1344 lacking a functional ramA were compared
ORGANISM(S): Salmonella enterica 
2009-12-31 | E-MEXP-2193 | biostudies-arrayexpress
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