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GenomicsSalt augments macrophage-driven host defense in the skin
Immune cells regulate a hypertonic microenvironment in the skin; however, possible functions of increased skin Na+ concentrations are unknown. We found that Na+ accumulated at the site of bacterial skin infections in humans and in mice. We used the protozoan parasite Leishmania (L.) major as a model...
ORGANISM(S): Mus musculus 
2015-02-26 | E-MTAB-3343 | biostudies-arrayexpress
GenomicsHigh salt reduces the activation of IL-4+IL-13 stimulated macrophages
High salt (NaCl) intake is a major risk factor for cardiovascular disease; high NaCl has also been shown to be a powerful modulator of pro-inflammatory immune cell polarization. To investigate the effect of high NaCl on the polarization of M(IL-4+IL-13) macrophages we performed gene expression analy...
ORGANISM(S): Mus musculus 
2015-02-07 | E-MTAB-3140 | biostudies-arrayexpress
ProteomicsKlein / Husselmann chia under salt and caffeic acid stress
Husselmann 2017: Following gel and TOF/TOF investigation of chia salinity stress by Achmat Williams [http://hdl.handle.net/11394/5650], Husselmann and Klein designed an LC-MS/MS experiment for five replicates in each of five cohorts: caffeic acid stress, salt stress, both stresses, and controls for ...
ORGANISM(S): Salvia Hispanica (ncbitaxon:49212) 
2021-02-12 | MSV000086861 | MassIVE
TranscriptomicsTranscription profiling of human prostate cancer cells, normal epithelial prostatic cells and stroma cells from patients in placebo, selenium, vitamin E or selenium and vitamin E treatment groups
85 radical prostatectomy specimens (where 16 samples are in Placebo group (PL), 15 are in Selenium group (SE), 25 are in Vitamin E group (VE) and 27 are in Vitamin E & Selenium group (VS.Treatment groups: l-selenomethionine, 400 ug + placebo (vitamin E); vitamin E, 400 IU + placebo (l-selenomethion...
ORGANISM(S): Homo sapiens 
2008-07-01 | E-MEXP-1327 | biostudies-arrayexpress
TranscriptomicsGene transcription profiles showing early systemic response to E. coli (k2bh2) infection in bovine liver
We studied the response to infection and associated perturbations to the bovine liver’s normal function by examining gene transcription data from liver biopsies collected following an E. coli infection in the udder of primiparous dairy cows. This is the first study to examine gene transcription resp...
ORGANISM(S): Bos taurus 
2012-01-01 | E-GEOD-25319 | biostudies-arrayexpress
TranscriptomicsComparative Genomic Hybridization of E. coli and Shigella species to determine the relatedness of isolates from Neobladders
Using comparative genomic hybridization we examined the genome content of 30 isolates of E. coli and Shigella to determine the relative location of E. coli isolates from the human neobladder Isolates were included in the study that represent the prototype strains of multiple pathovars. No replicate...
ORGANISM(S): Shigella sonnei 
2011-07-24 | E-GEOD-27326 | biostudies-arrayexpress
TranscriptomicsChromatin immunoprecipitation of Drosophila Schneider 2 cells using NELF-E and NELF-B antibodies
ChIP-chip analysis of GAGA factor and NELF in Drosophila S2 cells
ORGANISM(S): Drosophila melanogaster 
2008-04-04 | E-MEXP-1547 | biostudies-arrayexpress
TranscriptomicsPhotoperiodic control of smoltification
This experiment is intended to provide information about transcriptional changes in the gill of Atlantic salmon during smoltification, in comparison with juvenile salmon not given the appropriate photoperiodic stimuli. Also, transcriptional changes due to osmotic stress (24H salt water challenged) w...
ORGANISM(S): Salmo salar 
2019-09-12 | E-MTAB-8276 | biostudies-arrayexpress
TranscriptomicsComparison of the nucleotide-resolution, genome-wide, 5'-end maps of the transcriptomes of Escherichia coli K12 strain BW25113 and Streptomyces coelicolor A3(2) strain M145
The differential RNA-seq data contained within this entry is complemented by global RNA-seq. S. coelicolor and E. coli reference strains were grown in batch culture with shaking. The E. coli sample was extracted during mid-exponential growth, while the S. coelicolor sample was extracted at the start...
ORGANISM(S): Escherichia coli BW25113 
2013-05-01 | E-GEOD-46507 | biostudies-arrayexpress
TranscriptomicsTranscriptional profiling of E. coli cultures exposed to tellurite 0.5 µg/ml
E. coli cultures were exposed to tellurite 0.5 µg/ml during 15 min. Total RNA was extracted and cDNA labeled probes were generated by reverse transcription using Alexa 555 and Alexa 647 fluorophores. These probes were used to hybridize genomic slides containing genomic arrays to determine global tr...
ORGANISM(S): Escherichia coli K-12 
2014-07-30 | E-GEOD-58176 | biostudies-arrayexpress
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