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ProteomicsUnraveling the dual roles of MICAL2 in skeletal muscle physiology and fusion negative rhabdomyosarcoma tumor progression
Rhabdomyosarcoma (RMS) is a prevalent soft tissue sarcoma in pediatric populations characterized by dysregulated myogenesis and limited treatment options. Notably, fusion negative RMS (FN-RMS) constitutes the predominant subtype in pediatric patients and commonly harbors RAS mutations, resulting in ...
ORGANISM(S): Mus musculus (Mouse) 
2026-10-19 | PXD056474 | Pride
Rhabdomyosarcoma  skeletal muscle  mical2 
ProteomicsExtracellular vesicle-derived miRNAs improve stem cell-based therapeutic approaches in muscle wasting conditions.
Skeletal muscle holds an intrinsic capability of growth and regeneration both in physiological conditions and in case of injury. Chronic muscle illnesses, generally caused by genetic and acquired factors, lead to deconditioning of the skeletal muscle structure and function, and are associated with a...
ORGANISM(S): Mus musculus (Mouse) 
2022-11-09 | PXD035446 | Pride
Aging Mirna Muscular dystrophy Skeletal muscle Hypertrophy Extracellular vesicle 
TranscriptomicsAngiogenesis and Gene Signature in Muscular Hypertrophy
Adult myogenic progenitor cells (activated satellite cells) express both HGF and its receptor cMet. Following muscle injury, autocrine HGF-Met stimulation plays a key role in promoting activation and early division of satellite cells. Magic-F1 (Met-Activating Genetically Improved Chimeric Factor-1) ...
ORGANISM(S): Mus musculus 
2016-06-28 | E-GEOD-83771 | biostudies-arrayexpress
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