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Targeted proteomics has been playing an increasingly important role in hypothesis-driven protein research and clinical bi-omarker discovery. We have previously created a workflow, Tomahto, to enable real-time targeted pathway proteomics assays using two-dimensional multiplexing technology. Coupled w...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-08-14 | MSV000095604 | MassIVE
Sample multiplexing for retinal single-cell RNA-sequencing
Targeted proteomics enables hypothesis-driven research by measuring the cellular expression of protein cohorts related by function, disease, or class after perturbation. Here, we present a pathway-centric approach and an assay builder resource for targeting entire pathways of proteins selected from ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Mus Musculus (ncbitaxon:10090) 
2022-08-11 | MSV000090110 | MassIVE
Single cell RNA sequencing (ScRNA-seq) often requires sample pooling, but sample variance is rarely addressed. We perform scRNA-seq on retinal ganglion cells with retina-multiplexing to assess the whether this enables comparisons between retinas of an experiment.
ORGANISM(S): Mus musculus 
2024-06-12 | GSE254587 | GEO
CellTag Indexing: genetic barcode-based sample multiplexing for single-cell genomics
The yeast, Saccharomyces cerevisiae, is a widely used model system for investigating conserved biological functions and pathways. Advancements in sample multiplexing have facilitated the study of the yeast proteome, yet many yeast proteins remain uncharacterized or only partially characterized. The ...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2022-09-02 | PXD032042 | Pride
Sample multiplexing for joint RNA-ATAC multiomic profiling using MULTI-seq
Targeted proteomics plays a specialized role in hypothesis-driven research where the expression of cohorts of dozens of proteins related by function, disease, co-expression, localization, or class are measured after perturbing a pathway. Moreover, a major advance in proteomics is the ability to comb...
ORGANISM(S): Mus musculus (Mouse) 
2023-03-11 | PXD029461 | Pride
Targeted proteomics plays a specialized role in hypothesis-driven research where the expression of cohorts of dozens of proteins related by function, disease, co-expression, localization, or class are measured after perturbing a pathway. Moreover, a major advance in proteomics is the ability to comb...
ORGANISM(S): Mus musculus (Mouse) 
2023-03-11 | PXD033679 | Pride
Targeted proteomics plays a specialized role in hypothesis-driven research where the expression of cohorts of dozens of proteins related by function, disease, co-expression, localization, or class are measured after perturbing a pathway. Moreover, a major advance in proteomics is the ability to comb...
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD033643 | Pride
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