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ProteomicsA safe alternative to H37Rv: the attenuated double auxotroph Mycobacterium tuberculosis ΔleuDΔpanCD
Currently available model organisms such as Mycobacterium smegmatis and Mycobacterium bovis Bacillus Calmette-Guérin (BCG) have significantly contributed to our understanding of tuberculosis (TB) biology, these models have limitations such as differences in genome size, growth rates and virulence. A...
ORGANISM(S): Mycobacterium tuberculosis 
2019-07-30 | PXD013677 | Pride
Biosafety level 2 Model organism Mycobacterium tuberculosis Attenuated auxotroph 
TranscriptomicsAnalysis of colorectal tissue from APC- and MYH-associated polyposis patients
Expression profiling is a well established tool for the genome-wide analysis of the transcriptional activity of human neoplasia. However, the high sensitivity of this approach combined with the well-known cellular and molecular heterogeneity of cancer often result in extremely complex and extended e...
ORGANISM(S): Homo sapiens 
2008-04-01 | E-GEOD-9689 | biostudies-arrayexpress
TranscriptomicsTranscriptional reprogramming of engineered cellobiose-utilizing Saccharomyces cerevisiae in response to cellobiose revealed by RNA-Seq
Saccharomyces cerevisiae cannot metabolize cellobiose in nature. Here, S. cerevisiae was engineered to achieve cellobiose utilization by introducing both a cellodextrin transporter gene (cdt-1) and an intracellular β-glucosidase gene (gh1-1) from Neurospora crassa. We sequenced mRNA from anaerobic e...
ORGANISM(S): Saccharomyces cerevisiae 
2015-04-10 | E-GEOD-54825 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human dormant and angiogenic breast cancer, osteosarcoma, liposarcoma and brain tumor cell lines
The Goal of this study is to explore the transcriptional differences between angiogenic and non-angiogenic tumors generated in Dr. Folkman's Lab, Harvard Medical School.
Referneces:
Almog N, Henke V, Flores L, Hlatky L, Kung AL, Wright RD, Berger R, Hutchinson L, Naumov GN, Bender E, Akslen LA...
ORGANISM(S): Homo sapiens 
2009-02-03 | E-TABM-390 | biostudies-arrayexpress
ProteomicsPulse-chase SILAC of Mycobacterium tuberculosis infected THP-1 macrophages
Pulse chase SILAC was used to identify protein turnover within human macrophages infected with mycobacterium tuberculosis CDC1551, a ppe38-71 mutant strain, a complemented strain and an uninfected control.
ORGANISM(S): Homo sapiens (Human) 
2021-06-15 | PXD021166 | Pride
Lc-ms/ms Tuberculosis Silac Macrophages 
TranscriptomicsTranscription profiling of Mycobacterium tuberculosis using a transposon mutagenesis approach to elucidate pe/ppe regulation
Data is also available from BuG@Sbase
ORGANISM(S): Mycobacterium tuberculosis 
2009-08-18 | E-BUGS-91 | biostudies-arrayexpress
TranscriptomicsIntegrative genomics identifies novel associations with APOL1 risk genotype in African American NEPTUNE subjects
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series. This dataset is part of the TransQST collection.
ORGANISM(S): Homo sapiens 
2015-07-15 | E-GEOD-68127 | biostudies-arrayexpress
UnknownAssociations of serum trimethylamine N-oxide and its precursors with colorectal cancer risk in the Prostate, Lung, Colorectal, Ovarian Cancer Screening Trial Cohort.
Not available
S-EPMC11441407 | biostudies-literature
UnknownEML4-ALK Variant 3 Promotes Mitotic Errors and Spindle Assembly Checkpoint Deficiency Leading to Increased Microtubule Poison Sensitivity.
Not available
S-EPMC9381094 | biostudies-literature
TranscriptomicsTranscription profiling of primary human prostate cancer-associated fibroblasts
Primary human prostate fibroblast cultures were generated via an explant culture method from 4mm biopsies taken from radical prostatectomy samples of treatment-naive prostate cancer patients. The samples include partially patient-matched fibroblast cultures from benign- as well as cancer-associated ...
ORGANISM(S): Homo sapiens 
2025-09-02 | E-MTAB-13167 | biostudies-arrayexpress
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