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TranscriptomicsHigh-resolution profiling and analysis of viral and host small RNAs during human cytomegalovirus infection
Small RNA deep sequencing analysis was conducted on primary human fibroblasts infected with human cytomegalovirus (HCMV). HCMV-encoded miRNAs accumulated to ~20% of the total smRNA population at late stages of infection, and our analysis led to improvements in viral miRNA annotations and identificat...
ORGANISM(S): Homo sapiens 
2011-11-10 | E-GEOD-33584 | biostudies-arrayexpress
TranscriptomicsDrosophila Sex Hierarchy Regulated Gene Expression in 48 hour APF Pupae
Drosophila melanogaster undergoes a complete metamorphosis, during which time the larval male and female forms transition into sexually dimorphic, reproductive adult forms. To understand this complex morphogenetic process at a molecular-genetic level, we performed whole genome microarray analyses. ...
ORGANISM(S): Drosophila melanogaster 
2009-02-10 | E-GEOD-11311 | biostudies-arrayexpress
TranscriptomicsDrosophila Gene Expression During Metamorphosis in Wild Type and Germline Minus Pupae
Drosophila melanogaster undergoes a complete metamorphosis, during which time the larval male and female forms transition into sexually dimorphic, reproductive adult forms. To understand this complex morphogenetic process at a molecular-genetic level, we performed whole genome microarray analyses. G...
ORGANISM(S): Drosophila melanogaster 
2009-02-10 | E-GEOD-11313 | biostudies-arrayexpress
TranscriptomicsFRUM and EcR-regulated expression during Drosophila development
In Drosophila, male-specific FRU (FRUM) is required to establish the potential for courtship behaviors, but the downstream effectors of FRUM during development are largely unknown. A microarray-based approach identified genes that are differentially expressed as a consequence of FRUM in pupae, in b...
ORGANISM(S): Drosophila melanogaster 
2009-09-21 | E-GEOD-11752 | biostudies-arrayexpress
GenomicsChIP-seq for the identification of enhancer and super enhancers in Acute Myeloid Leukemia cells with a 3q-aberration
To infer enhancers and super enhancers in Acute Myeloid Leukemia (AML) Cell lines with a 3q-aberration we determined regions enriched for H3K27AC, H3K4ME3, H3K4ME1, P300, and BRD4 in MOLM1. Additionally we determined regions enriched for P300 and BRD4 in the cell line Mutz3 which also harbors a 3q-a...
ORGANISM(S): Homo sapiens 
2014-04-03 | E-MTAB-2224 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Aedes infected with alphavirus, Sindbis (MRE16 Malaysian strain)
The midgut of hematophagous insects is the initial site of infection by arthropod-borne viruses (arboviruses) and plays a crucial role in vector competence. To further understand processes that occur in the midgut in response to infection by an arbovirus, DNA microarrays were used to analyze gene ex...
ORGANISM(S): Aedes aegypti 
2005-08-01 | E-MEXP-381 | biostudies-arrayexpress
TranscriptomicsHuman thyroid adenomas, carcinomas, and normals
Human samples of various thyroid carcinomas, adenomas, and normals, each from a different patient, had mRNA assays performed using Affymetrix HG_U133A arrays, with 22283 probe-sets. The 99 samples consisted of 4 normals, 10 follicular adenomas, 13 follicular carcinomas, 7 oncocytic adenomas, 8 onco...
ORGANISM(S): Homo sapiens 
2011-02-09 | E-GEOD-27155 | biostudies-arrayexpress
TranscriptomicsTranscription profiling rat hepatic cell ines WB-F344 and WB311 treated with rapamycin
Two rat hepatic cell lines, WB-F344 and WB311, were characterized for the effect of rapamycin on gene expression. The WB311 cell line, which is tumorigenic and resistant to the growth inhibitory effects of rapamycin, was originally derived from the WB-F344 parental hepatic epithelial cell line. Th...
ORGANISM(S): Rattus norvegicus 
2009-09-25 | E-GEOD-17661 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse Icmt+/+ and Icmt-/- embryonic fibroblasts cells
Comparison of gene expression profiles of Icmt+/+ and Icmt-/- cells
ORGANISM(S): Mus musculus 
2007-01-08 | E-MEXP-540 | biostudies-arrayexpress
TranscriptomicsMale breast cancer copy number profiles
Exploratory study of copy number profiles of male breast cancer patients. The experiment contains 75 male breast cancer samples, analysed on a 135K whole genome CGH array
ORGANISM(S): Homo sapiens 
2015-09-13 | E-GEOD-57087 | biostudies-arrayexpress
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