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UnknownmTORC1 activity is essential for erythropoiesis and B cell lineage commitment.
Not available
S-EPMC6858379 | biostudies-literature
UnknownThe extracellular matrix controls stem cell specification and crypt morphology in the developing and adult mouse gut.
Not available
S-EPMC9713296 | biostudies-literature
UnknownRelA regulates CXCL1/CXCR2-dependent oncogene-induced senescence in murine Kras-driven pancreatic carcinogenesis.
Not available
S-EPMC4966329 | biostudies-literature
UnknownMouse Ovarian Cancer Models Recapitulate the Human Tumor Microenvironment and Patient Response to Treatment.
Not available
S-EPMC6963791 | biostudies-literature
UnknownPhenotypic plasticity underlies local invasion and distant metastasis in colon cancer.
Not available
S-EPMC8192123 | biostudies-literature
ProteomicsMetabolic profiling stratifies colorectal cancer and reveals adenosylhomocysteinase as a therapeutic target
The genomic landscape of colorectal cancer (CRC) is shaped by inactivating mutations in tumour suppressors such as APC, and oncogenic mutations such as mutant KRAS. Here we used genetically engineered mouse models (GEMMs), and multimodal mass spectrometry-based metabolomics to study the impact of co...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Mus Musculus (ncbitaxon:10090) 
2023-07-18 | MSV000092468 | MassIVE
UnknownHIRA orchestrates a dynamic chromatin landscape in senescence and is required for suppression of neoplasia.
Not available
S-EPMC4265675 | biostudies-literature
MetabolomicsGNPS - Metabolic profiling stratifies colorectal cancer and reveals adenosylhomocysteinase as a therapeutic target
The genomic landscape of colorectal cancer (CRC) is shaped by inactivating mutations in tumour suppressors such as APC, and oncogenic mutations such as mutant KRAS. Here we used genetically engineered mouse models (GEMMs), and multimodal mass spectrometry-based metabolomics to study the impact of co...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Mus Musculus (ncbitaxon:10090) 
2023-07-18 | MSV000092468 | GNPS
TranscriptomicsGene expression profiling along the intestinal crypt axis.
The identification of Lgr5 as an intestinal stem cell marker has made it possible to isolate and study primary intestinal stem cells. Transcriptional differences between intestinal stem cells can be explored by the use of the Lgr5-eGFP-ires-CreERT2 knock-in mouse. In this mouse model GFP expression ...
ORGANISM(S): Mus musculus 
2012-08-15 | E-GEOD-36497 | biostudies-arrayexpress
UnknownE-cadherin can limit the transforming properties of activating β-catenin mutations.
Not available
S-EPMC4570519 | biostudies-literature
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