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MetabolomicsEpithelial-Cell-Derived Phospholipase A2 Group 1B Is an Endogenous Anthelmintic
Immunity to intestinal helminth infections has been well studied, but the mechanism of helminth killing prior to expulsion remains unclear. Here we identify epithelial-cell-derived phospholipase A2 group 1B (PLA2g1B) as a host-derived endogenous anthelmintic. PLA2g1B is elevated in resistant mice an...
2018-08-13 | MTBLS523 | MetaboLights
TranscriptomicsDistinct transcriptional outputs associated with mono- and di-methylated histone H3 arginine 2
Dimethylation of histone H3 arginine 2 (H3R2me2) maintains transcriptional silencing by inhibiting Set-1 mediated trimethylation of H3K4. Here we demonstrate that arginine 2 is also monomethylated (H3R2me1) in yeast but that its functional characteristics are distinct from H3R2me2: (a) H3R2me1 does ...
ORGANISM(S): Saccharomyces cerevisiae 
2010-05-06 | E-GEOD-14453 | biostudies-arrayexpress
UnknownEmpirical Rescue Eradication Therapy for Helicobacter pylori Infection in Second and Subsequent Treatment Lines: Experience From 500 Cases of the Brazilian Registry on H. pylori Management (Hp-BrazilReg).
Not available
S-EPMC12521799 | biostudies-literature
GenomicsChIP-Seq experiment of Mcm2-HA in wild type and H3K37R yeast cells
This ChIP-Seq experiment profiles Mcm2 binding to chromatin in wild type yeast cells and in cells with the K37R mutation in histone H3
ORGANISM(S): Saccharomyces cerevisiae S288C 
2021-04-28 | E-MTAB-9070 | biostudies-arrayexpress
TranscriptomicsChIP-Seq of yeast MCM2 in a time-course experiment after release from the G1 cell-cycle phase
ChIP-Seq experiment of MCM2 binding to chromatin in a time-course experiment after release from the G1 cell-cycle phase
ORGANISM(S): Saccharomyces cerevisiae S288C 
2021-04-28 | E-MTAB-9071 | biostudies-arrayexpress
GenomicsChIP-Seq of yeast H3K37me1 in a time-course experiment after release from the G1 cell-cycle phase
This experiment measured the mono-methylation of lysine 37 of histone H3 in yeast cells at various phases of the cell cycle (G1, G1/S and S).
ORGANISM(S): Saccharomyces cerevisiae S288C 
2021-04-28 | E-MTAB-9058 | biostudies-arrayexpress
GenomicsA SNF2 protein targets variable copy number repeats and thereby influences allele-specific expression
ATRX is an X-linked gene of the SWI/SNF family whose role in vivo is currently unknown. Mutations in ATRX cause syndromal mental retardation. ATRX binds to tandem repeat (TR) sequences both in heterochromatin (e.g. telomeres) and euchromatin. Genes associated with these TRs can be dysregulated when ...
ORGANISM(S): Homo sapiens 
2010-11-02 | E-GEOD-22162 | biostudies-arrayexpress
TranscriptomicsAnalysis of the effect of acid stress in Lactococcus lactis MG1363
To understand the system response to pH changes in the environment, the expression of genes during the pH shift was investigated. Pre-adaptation effects were examined by comparing the effects seen with cells pre-grown in pH 5.1 or pH 6.5 to those occuring after a sudden pH change (pre-grown in pH 6....
ORGANISM(S): Lactococcus lactis subsp. cremoris MG1363 
2013-05-17 | E-GEOD-47012 | biostudies-arrayexpress
UnknownZika Virus Surveillance at the Human-Animal Interface in West-Central Brazil, 2017-2018.
Not available
S-EPMC6950091 | biostudies-literature
UnknownResuscitation fluid practices in Brazilian intensive care units: a secondary analysis of Fluid-TRIPS.
Not available
S-EPMC8275089 | biostudies-literature
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