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MetabolomicsRepurposing the orphan drug nitisinone to control the transmission of African trypanosomiasis
Tsetse transmit African trypanosomiasis, which is a disease fatal to both humans and animals. A vaccine to protect against this disease does not exist so transmission control relies on eliminating tsetse populations. Although neurotoxic insecticides are the gold standard for insect control, they neg...
2021-10-06 | MTBLS2166 | MetaboLights
UnknownHigh-Density Autologous Chondrocyte Implantation as Treatment for Ankle Osteochondral Defects.
Not available
S-EPMC8236657 | biostudies-literature
ProteomicsProteomics of Pseudomonas sp. M1 and evolved lineages
Comparative proteomics of Pseudomonas sp. M1 wt vs myrcene-evolved lineages: M2C19 and M3C22 and impact of deletion of fleQ.
ORGANISM(S): Pseudomonas sp. M1 
2026-04-14 | PXD072045 | Pride
TranscriptomicsPeripheral tissue instruction is the primary determinant of CD8+ T cell pathogenicity: transcription profiling by RNA-seq of CD8+ effector T cells isolated from the blood and skin of HSCT patients developing acute pattern GVHD.
To determine whether murine GVHD associated tissue-specific signatures of donor CD8+ effector T cells are conserved at the same locations in humans developing GVHD, we compared the transcriptional profile of CD8+ T cells obtained simultaneously from the blood and skin of 5 patients developing acute ...
ORGANISM(S): Homo sapiens 
2018-03-28 | E-MTAB-5381 | biostudies-arrayexpress
TranscriptomicsPeripheral tissue instruction is the primary determinant of CD8+ T cell pathogenicity: transcription profiling by array of donor CD8+ effector T cells isolated from the secondary lymphoid organs, blood and GVHD-target organs at D+7 post-transplant (FTY720)
This study reports the evolution of the donor CD8 effector T cell transcriptomes at multiple sites and time points within the same host following allo-SCT. Donor derived CD8+ T cells were flow sorted from multiple organs in mice developing GVHD in two clinically relevant murine models of H-2b MHC-ma...
ORGANISM(S): Mus musculus 
2018-03-28 | E-MTAB-5380 | biostudies-arrayexpress
UnknownRandomized controlled trial comparing open anterograde anatomic radical retropubic prostatectomy with retrograde technique.
Not available
S-EPMC10023527 | biostudies-literature
UnknownA low molecular weight OLED material: 2-(4-((2-hydroxyethyl)(methyl)amino)benzylidene)malononitrile. Synthesis, crystal structure, thin film morphology, spectroscopic characterization and DFT calculations.
Not available
S-EPMC9071261 | biostudies-literature
UnknownHuman plasma plasminogen internalization route in Plasmodium falciparum-infected erythrocytes.
Not available
S-EPMC7449074 | biostudies-literature
TranscriptomicsRedirection of therapeutic T cells to a bone marrow niche improves their persistence and anti-tumor functions: transcription profiling by array of resting memory OT-I T_CXCR4) or OT-I T_Control cells isolated from the spleen 90 days following DC vaccination.
This study reports the improvement in function and antitumor efficacy of CXCR4 overexpression in therapeutic CD8+ T cells. Polyclonal CD8+ T cells from OT-I C57BL/6 (B6) mice were transduced with a modified pMP71 retroviral vector containing murine Cxcr4 and Gfp reporter sequences (T_CXCR4) or with ...
ORGANISM(S): Mus musculus 
2018-03-28 | E-MTAB-6091 | biostudies-arrayexpress
TranscriptomicsPeripheral tissue instruction is the primary determinant of CD8+ T cell pathogenicity: transcription profiling by array of donor CD8+ effector T cells isolated from the secondary lymphoid organs, blood and GVHD-target organs at D+6 post-transplant (B6>129 model)
This study reports the evolution of the donor CD8 effector T cell transcriptomes at multiple sites and time points within the same host following allo-SCT. Donor derived CD8+ T cells were flow sorted from multiple organs in mice developing GVHD in two clinically relevant murine models of H-2b MHC-ma...
ORGANISM(S): Mus musculus 
2017-01-16 | E-MTAB-5378 | biostudies-arrayexpress
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