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MetabolomicsDeficient Endoplasmic Reticulum-Mitochondrial Phosphatidylserine Transfer Causes Liver Disease
Non-alcoholic fatty liver is the most common liver disease worldwide. Here, we show that the mitochondrial protein mitofusin 2 (Mfn2) protects against liver disease. Reduced Mfn2 expression was detected in liver biopsies from patients with non-alcoholic steatohepatitis (NASH). Moreover, reduced Mfn2...
2018-01-25 | MTBLS600 | MetaboLights
TranscriptomicsGlobal variation of gene expression induced by constitutive activation of the NIK receptor in Arabidopsis
Arabidopsis was transformed with the NIK receptor or the mutant T474D NIK receptor and infected with CaLCuV. The global variation of gene expression was analysed by RNA-seq at 10 days post inoculation and 20 days post inoculation and differential gene expression was determinated in comparison with m...
ORGANISM(S): Arabidopsis thaliana 
2014-04-21 | E-GEOD-56922 | biostudies-arrayexpress
ModelsBenito-Vaquerizo2022- Anaerotignum neopropionicum DSM 3847 model
This project contains the first genome-scale metabolic model of Anaerotignum neopropionicum DSM 3847.
2024-04-10 | MODEL2201310001 | BioModels
FROG 
UnknownSpinocerebellar Ataxias: Phenotypic Spectrum of PolyQ versus Non-Repeat Expansion Forms.
Not available
S-EPMC11585503 | biostudies-literature
Unknown"Pink power"-the importance of coralline algal beds in the oceanic carbon cycle.
Not available
S-EPMC11436964 | biostudies-literature
TranscriptomicsConstitutive activation of the receptor-like kinase NIK impairs translation and confers tolerance to begomovirus infection
To generate an efficient defense against begomovirus, we modulated the activity of the immune defense receptor NIK (NSP-Interacting Kinase) in tomato plants; NIK is a virulence target of the begomovirus NSP during infection. Replacing threonine-474 with aspartate (T474D) within the kinase activation...
ORGANISM(S): Solanum lycopersicum 
2013-12-17 | E-GEOD-38028 | biostudies-arrayexpress
UnknownIdentification of Transporter Polymorphisms Influencing Metformin Pharmacokinetics in Healthy Volunteers.
Not available
S-EPMC10053761 | biostudies-literature
TranscriptomicsDifferential gene expression analysis in Enchytraeus albidus exposed to natural and chemical stressors at different exposure periods
The soil oligochaete Enchytraeus albidus is a standard test organism used in biological testing for Environmental Risk Assessment (ERA). Although effects are known at acute and chronic level, through survival, reproduction and avoidance behaviour endpoints, very little is known at the sub-cellular a...
ORGANISM(S): Enchytraeus albidus 
2011-08-31 | E-GEOD-26896 | biostudies-arrayexpress
TranscriptomicsIncomplete DNA methylation underlies a transcriptional memory of somatic cells in human iPS cells
Human induced pluripotent stem (iPS) cells are remarkably similar to embryonic stem (ES) cells, but recent reports indicate that there may be important differences between them. We carried out a systematic comparison of human iPS cells generated from hepatocytes (representative of endoderm), skin fi...
ORGANISM(S): Homo sapiens 
2011-04-17 | E-GEOD-23034 | biostudies-arrayexpress
TranscriptomicsGene expression in IGROV1 SP and non-SP cells
Side populations have recently been identified in ovarian cancers and may play an important role in post treatment relapse and resistance to chemotherapeutic drugs. In this study, we aimed to identify the differential expression between IGROV1 SP and NSP on Affymetrix HG-U133plus2 microarrays. We fo...
ORGANISM(S): Homo sapiens 
2011-02-09 | E-GEOD-25191 | biostudies-arrayexpress
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