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ProteomicsProteomic Analysis of the E6 Interactome in Response to Anisomelic Acid Treatment
Human papillomavirus (HPV) is a well-known cause of cervical cancer, with the viral oncoprotein E6 playing a key role in carcinogenesis. We previously showed that anisomelic acid treatment reduces E6 protein levels in HPV-positive cancer cells. In this study, we used mass spectrometry-based proteomi...
ORGANISM(S): Homo sapiens (Human) 
2025-09-22 | PXD065382 | Pride
Lc-ms/ms Anisomelic acid Normal oral keratinocytes Hpv16 e6 
ProteomicsMass spectrometry-based profiling of HDF, HDF Vim -/-, and their EVs, and the impact of these EVs on MCF7 and MCF10A proteomes
Vimentin is a well-established intracellular regulator of epithelial-mesenchymal transition (EMT). Recent studies have highlighted the role of extracellular vimentin from fibroblast-derived extracellular vesicles (EVs) in promoting wound healing and other functions. Building on these findings, we in...
ORGANISM(S): Homo sapiens (Human) 
2025-07-10 | PXD060764 | Pride
Extracellular vesicles Extracellular vimentin Lc-ms/ms 
ProteomicsHPV16 E7 Interactome Proteomics After Anisomelic Acid Treatment
Human papillomavirus (HPV) is a major cause of cervical and other anogenital cancers, with the viral oncoprotein E6 playing a central role in carcinogenesis. We previously demonstrated that anisomelic acid treatment reduces E7 protein levels in HPV-positive cancer cells. Here, we employed mass spect...
ORGANISM(S): Homo sapiens (Human) 
2025-12-10 | PXD069948 | Pride
Lc-ms/ms Anisomelic acid Normal oral keratinocyte Hpv16 e6 
MetabolomicsCesarean section alters the postnatal development of the gut microbiome and metabolome of male Wistar rats

Background: The gut microbiome, a complex community of bacteria, viruses, fungi, and protozoa, matures alongside its host. In humans, the birth mode, vaginal delivery (VD) or cesarean section (CS), is a major determinant of early microbial colonization. However, it remains unclea...

2026-07-30 | MTBLS7384 | MetaboLights
UnknownCharacterization of neurologic disease-associated <i>Streptococcus suis</i> strains within the United States swine herd and use of diagnostic tools.
Not available
S-EPMC11562895 | biostudies-literature
UnknownEarly Treatment with Pegylated Interferon Lambda for Covid-19.
Not available
S-EPMC9933926 | biostudies-literature
UnknownParkinson's Disease Gene Screening in Familial Cases from Central and South America.
Not available
S-EPMC11490405 | biostudies-literature
UnknownSex differences in the diagnosis latency of Parkinson's disease in Latin America.
Not available
S-EPMC12703624 | biostudies-literature
UnknownPara-infectious brain injury in COVID-19 persists at follow-up despite attenuated cytokine and autoantibody responses.
Not available
S-EPMC10746705 | biostudies-literature
UnknownEffectiveness of therapeutic heparin versus prophylactic heparin on death, mechanical ventilation, or intensive care unit admission in moderately ill patients with covid-19 admitted to hospital: RAPID randomised clinical trial.
Not available
S-EPMC8515466 | biostudies-literature
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