The main objectives were to validate the DNA array technology and establish the degree of correlation between any compound-induced effects on gene expression with those at the level of histological examination.
We performed a microarray analysis to compare the expression profile of azurin treated and untreated with different P-cadherin expression levels. We also compared the differentially expressed genes regulated by P-cadherin overexpression. Both cell lines presented an up-regulation of apoptosis mediat...