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UnknownCost-Effectiveness of Therapeutic Drug Monitoring of Anti-TNF Therapy in Inflammatory Bowel Disease: A Systematic Review
Not available
S-EPMC9145467 | biostudies-literature
UnknownEffects of an 8-month exercise intervention on physical capacity, NT-proBNP, physical activity levels and quality of life data in patients with pulmonary arterial hypertension by NYHA class.
Not available
S-EPMC5367801 | biostudies-literature
UnknownAccumulation of partly folded states in the equilibrium unfolding of the pneumococcal choline-binding module C-LytA.
Not available
S-EPMC1134977 | biostudies-literature
TranscriptomicsBisphosphonate related osteonecrosis of the jaw is associated with polymorphisms of the cytochrome P450 CYP2C8 in MM
We have explored the potential role of genetics in the development of osteonecrosis of the jaw (ONJ) in multiple myeloma (MM) patients under bisphosphonate therapy. A genome wide association study was performed using 500.568 single nucleotide polymorphisms (SNPs) in two series of homogeneously treat...
ORGANISM(S): Homo sapiens 
2008-09-25 | E-GEOD-11948 | biostudies-arrayexpress
TranscriptomicsThe cellular origin and malignant transformation of Waldenström's Macroglobulinemia [copy number variation]
Although information on the molecular pathogenesis of Waldenström’s Macroglobulinemia (WM) has greatly improved in recent years, the exact cellular origin and the mechanisms behind WM transformation from IgM MGUS remain undetermined. Here, we undertook an integrative phenotypic, molecular and genomi...
ORGANISM(S): Homo sapiens 
2015-05-06 | E-GEOD-61650 | biostudies-arrayexpress
TranscriptomicsRestoration of miR-214 expression reduces cell growth of myeloma cells through a positive regulation of P53 and inhibition of DNA replication
MicroRNAs have been demonstrated to be deregulated in multiple myeloma (MM). We have previously reported the downregulation of miR-214 in MM compared to normal plasma cells. In the present study, we have explored the functional role of miR-214 in myeloma pathogenesis. Ectopic expression of miR-214 r...
ORGANISM(S): Homo sapiens 
2012-12-28 | E-GEOD-35948 | biostudies-arrayexpress
UnknownThe Masked Polar Group Incorporation (MPGI) Strategy in Drug Design: Effects of Nitrogen Substitutions on Combretastatin and Isocombretastatin Tubulin Inhibitors.
Not available
S-EPMC6930638 | biostudies-literature
TranscriptomicsThe cellular origin and malignant transformation of Waldenström's Macroglobulinemia [gene expression]
Although information on the molecular pathogenesis of Waldenström’s Macroglobulinemia (WM) has greatly improved in recent years, the exact cellular origin and the mechanisms behind WM transformation from IgM MGUS remain undetermined. Here, we undertook an integrative phenotypic, molecular and genomi...
ORGANISM(S): Homo sapiens 
2015-05-05 | E-GEOD-61597 | biostudies-arrayexpress
UnknownExosomal biomarkers and therapeutics in lung cancer: a narrative review on their role in early detection and targeted treatment.
Not available
S-EPMC12683418 | biostudies-literature
UnknownCrystallization and preliminary X-ray diffraction studies of the transcriptional repressor PaaX, the main regulator of the phenylacetic acid degradation pathway in Escherichia coli W.
Not available
S-EPMC3212382 | biostudies-literature
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