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UnknownFunctional characterization of a CDKN1B mutation in a Sardinian kindred with multiple endocrine neoplasia type 4 (MEN4).
Not available
S-EPMC5713151 | biostudies-literature
ProteomicsProtein Kinase C activation regulates NDRG1 expression
N-myc downstream regulated gene 1 (NDRG1) is a member of the NDRG family of intracellular proteins, and plays a central role in a wide range of biological processes including stress response, differentiation, and maintenance of the myelin sheath. The overexpression of NDRG1 is an indicator of poor p...
ORGANISM(S): Homo sapiens (Human) 
2025-05-06 | PXD045164 | Pride
Tnbc Breast cancer Pkc Ndrg1 
UnknownUnraveling the protein kinase C/NDRG1 signaling network in breast cancer.
Not available
S-EPMC11686873 | biostudies-literature
UnknownA New Bioassay Platform Design for the Discovery of Small Molecules with Anticancer Immunotherapeutic Activity.
Not available
S-EPMC7760914 | biostudies-literature
UnknownMechanical transduction of cytoplasmic-to-transmembrane-domain movements in a hyperpolarization-activated cyclic nucleotide-gated cation channel.
Not available
S-EPMC6102142 | biostudies-literature
GenomicsGenome wide profiling of RNA Polymerase II upon knock-down or overexpression of RECQL5
RECQL5 globally effects the distribution of RNA Polymerase II on genes in a dose dependent manner. Knock-down of RECQL5 reduces RNA Polymerase II density in the gene body, while increasing density on TSS and TTS. Overexpression shows exactly the opposite effect. We postulate that RECQL5 acts as a...
ORGANISM(S): Homo sapiens 
2014-06-09 | E-GEOD-49008 | biostudies-arrayexpress
TranscriptomicsMapping of nascent RNA upon release of DRB in WT and KD of RECQL5
Global Run-On has been performed on WT or KD for RECQL5 cells after release from DRB. When RECQL5 is knocked-down the transcriptional wave front is more advanced, suggesting that transcription is faster. Constitutive knock-down cell lines expressing or not endogenous levels of shRNA resistant RECQL...
ORGANISM(S): Homo sapiens 
2014-06-09 | E-GEOD-49133 | biostudies-arrayexpress
UnknownRational design of a mutation to investigate the role of the brain protein TRIP8b in limiting the cAMP response of HCN channels in neurons.
Not available
S-EPMC7478871 | biostudies-literature
UnknownTumor Infiltrating Lymphocytes and NHERF1 Impact on Prognosis of Breast Cancer Patients.
Not available
S-EPMC6931214 | biostudies-literature
UnknownA reduced mechanical model for cAMP-modulated gating in HCN channels.
Not available
S-EPMC5225470 | biostudies-literature
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