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TranscriptomicsExpression data of MIAPaCa-2 cells transfected with NDRG1
NDRG1 functions as a metastasis suppressor in pancreatic and other cancers. To determine the molecular function of NDRG1 in MIAPaCa-2 pancreatic cancer cells, we performed a whole genome gene array analysis on these cells stably transfected with NDRG1 when compared to empty vector-transfected contro...
ORGANISM(S): Homo sapiens 
2011-07-22 | E-GEOD-25086 | biostudies-arrayexpress
ProteomicsMapping the interactome of OSCC prognostic-associated proteins NDRG1 and PGK1 through proximity labeling using TurboID
Oral squamous cell carcinoma (OSCC) is a prevalent type of head and neck cancer, accounting for more than 90% of all oral malignancies worldwide. The identification of diagnostic and prognostic markers for OSCC is crucial for improving patient outcomes, as early detection and treatment are critical ...
ORGANISM(S): Homo sapiens (Human) 
2025-05-06 | PXD048046 | Pride
Ndrg1 Oral cancer Pgk1 Turboid Interactome Proximity labeling Prognostic 
TranscriptomicsEffect of NDRG1 deletion and hypoxia in mouse placenta
We sought to identify changes in placental gene expression that may contribute to the phenotype of NDRG1-deficient embryos, and to define the contribution of hypoxia and fetal sex to these changes. We therefore used high-density oligonucleotide microarrays to interrogate differences in placental gen...
ORGANISM(S): Mus musculus 
2013-04-26 | E-GEOD-46381 | biostudies-arrayexpress
ProteomicsProtein Kinase C activation regulates NDRG1 expression
N-myc downstream regulated gene 1 (NDRG1) is a member of the NDRG family of intracellular proteins, and plays a central role in a wide range of biological processes including stress response, differentiation, and maintenance of the myelin sheath. The overexpression of NDRG1 is an indicator of poor p...
ORGANISM(S): Homo sapiens (Human) 
2025-05-06 | PXD045164 | Pride
Tnbc Breast cancer Pkc Ndrg1 
Genomicsexpression data from NDRG1 depleted SKBR3 cells
expression data from NDRG1 depleted SKBR3 cells
PRJNA449286 | ENA
TranscriptomicsNDRG1 siRNA and overexpression in breast cell lines
N-myc downstream-regulated gene 1 (*NDRG1*) is induced by cellular stress such as hypoxia and DNA damage, and in humans, germ line mutations cause Charcot-Marie-Tooth disease. However, the roles of NDRG1 in the cell are not fully understood. Previously, NDRG1 was shown to mediate doxorubicin resista...
ORGANISM(S): Homo sapiens 
2011-11-04 | E-GEOD-33437 | biostudies-arrayexpress
TranscriptomicsGlobal gene expression analysis reveals a link between NDRG1 and vesicle transport.
This SuperSeries is composed of the following subset Series: GSE33437: NDRG1 siRNA and overexpression in breast cell lines GSE33438: MCF-7 and ZR-75-1 cell lines hypoxia Refer to individual Series
ORGANISM(S): Homo sapiens 
2011-11-04 | E-GEOD-33439 | biostudies-arrayexpress
TranscriptomicsNDRG1 siRNA and overexpression in breast cell lines
N-myc downstream-regulated gene 1 (*NDRG1*) is induced by cellular stress such as hypoxia and DNA damage, and in humans, germ line mutations cause Charcot-Marie-Tooth disease. However, the roles of NDRG1 in the cell are not fully understood. Previously, NDRG1 was shown to mediate doxorubicin resista...
ORGANISM(S): Homo sapiens 
2011-11-04 | GSE33437 | GEO
Transcriptomicsexpression data from NDRG1 depleted SKBR3 cells
SKBR3 cells expressing NDRG1 shRNA1 or vector control were harvested by trypsinization and total RNA was extracted. Silencing NDRG1 reduces cell proliferation rates, causing lipid metabolism dysfunction including increased fatty acid incorporation into neutral lipids and lipid droplets. global chang...
ORGANISM(S): Homo sapiens 
2018-06-21 | GSE112841 | GEO
TranscriptomicsExpression data of MIAPaCa-2 cells transfected with NDRG1
NDRG1 functions as a metastasis suppressor in pancreatic and other cancers. To determine the molecular function of NDRG1 in MIAPaCa-2 pancreatic cancer cells, we performed a whole genome gene array analysis on these cells stably transfected with NDRG1 when compared to empty vector-transfected contro...
ORGANISM(S): Homo sapiens 
2011-07-23 | GSE25086 | GEO
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