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ProteomicsMacrophage infectivity potentiator protein, a peptidyl prolyl cis/trans isomerase, essential for Coxiella burnetii growth and pathogenesis
Coxiella burnetii is a Gram-negative intracellular pathogen that causes the debilitating disease Q fever, which affects both animals and humans. The only available vaccine, Q-Vax, is effective but has a high risk of severe adverse reactions, limiting its use as a countermeasure to contain outbreaks....
ORGANISM(S): Coxiella burnetii Dugway 5J108-111 
2023-06-15 | PXD036679 | Pride
Proteomics Coxiella Peptidyl prolyl cis/trans isomerase 
ProteomicsTrigger Factor in Burkholderia pseudomallei is essential for key virulence determinants including host cell internalisation, cytotoxicity, motility and stress resistance.
Melioidosis is a potentially fatal infection caused by Burkholderia pseudomallei, a bacterium that is intrinsically resistant to many commonly used antibiotics. Therefore, the identification of new drug targets is essential for the development of new and effective therapies. This study demonstrates...
ORGANISM(S): Burkholderia pseudomallei (strain K96243) 
2026-04-07 | PXD067556 | Pride
Lfq Burkholderia pseudomallei 
ProteomicsRole of ppiB in burkholderia pseudomallei
Burkholderia pseudomallei is the causative agent of melioidosis a disease endemic in South-East Asia and Northern Australia. The mortality rates in these areas are unacceptably high even with antibiotic treatment, attributed to intrinsic and acquired resistance of B. pseudomallei to antibiotics. Wi...
ORGANISM(S): Burkholderia pseudomallei 
2019-08-05 | PXD012956 | Pride
Burkholderia pseudomallei Lfq Proteomics 
TranscriptomicsRotating wall vessel (RWV) grown A549s compared to monolayer grown A549s
A549 epithelial cells grown under two different conditions were compared. A549s grown in rotating wall vessel cultures disp[lay a more in-vivo like phenotype. The data here describe the transcriptional differences between the two culture methods 1 colour; Cy3 labelled, 5 biological replicates for e...
ORGANISM(S): Homo sapiens 
2012-10-01 | E-GEOD-36931 | biostudies-arrayexpress
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