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ProteomicsAnalysis of SARS-CoV-2 S and human ACE2 protein by LC-MS
Analysis of intact N-linked glycopeptides for SARS-Cov-2 S and huamn ACE2 protein by LC-MS
ORGANISM(S): Severe acute respiratory syndrome coronavirus 2 
2020-09-09 | PXD019937 | Pride
Sars-cov-2 s ace2 n-glycopeptide lc-ms 
ProteomicsA Linkage- Specific Sialic Acid Labeling Strategy Reveals Different Site-Specific Glycosylation Patterns in SARS-CoV-2 Spike Protein Produced in CHO and HEK Cell Substrates
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus utilizes an extensively glycosylated spike protein that protrudes from the viral envelope to bind to angiotensin-converting enzyme-related carboxypeptidase (ACE2) as its primary receptor to mediate host-cell entry. Currently, the...
ORGANISM(S): Homo sapiens (Human) Cricetulus barabensis 
2022-02-17 | PXD027536 | Pride
Lc-msms Glycopeptide Recombinant sars-2 spike Sialic acids labeling 
ProteomicsIn planta deglycosylation improves the SARS-CoV-2 neutralization activity of recombinant ACE2-Fc
The ectodomain of human ACE2-Fc was transiently expressed in leaves of Nicotiana benthamiana plants and protein A and SEC purified. SEC-purified ACE2-Fc was sequentially digested with chymotrypsin and trypsin and the glycopeptides were subjected to LC-ESI-MS analysis using the LC-OTMS, Orbitrap Expl...
ORGANISM(S): Nicotiana benthamiana 
2023-04-18 | PXD041320 | Pride
Recombinant protein Glycosylation Nicotiana benthamiana Glycoprotein 
ProteomicsRe-analysis of glycoproteomics data with Glyco-Decipher
Reanalysis of submissions PXD005411, PXD005413, PXD005412, PXD005553, PXD005555, PXD005565 and PXD019937 using Glyco-Decipher. Identification results of peptide-spectrum matches supporting Glyco-Decipher manuscript (Glyco-Decipher: glycan database-independent peptide matching enables discovery of ne...
ORGANISM(S): Mus musculus (Mouse) Saccharomyces cerevisiae (Baker's yeast) 
2022-03-04 | PXD031032 | Pride
Glycoproteomics  glycopeptide  reanalysis  glycosylation  n-glycosylation 
ProteomicsCharacterization of site-specific O- and N-glycopeptides from recombinant spike and ACE2 glycoproteins using LC-MS/MS analysis
The COVID-19 pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has resulted in millions of infections and deaths globally. Although vaccination campaigns are mitigating the pandemic, emerging viral variants continue to pose challenges. The spike (S) protein of SARS-Co...
ORGANISM(S): Sars Coronavirus (ncbitaxon:227859) Homo Sapiens (ncbitaxon:9606) 
2024-11-13 | MSV000096403 | MassIVE
ProteomicsStructural and Functional Glycosylation of the Abdala COVID-19 Vaccine
Abdala is a COVID-19 vaccine produced in Pichia pastoris and is based on the receptor-binding domain (RBD) of the SARS-CoV-2 spike. Abdala is currently approved for use in multiple countries with clinical trials confirming its safety and efficacy in preventing severe illness and death. Although P. p...
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD058644 | Pride
Glycosylation Covid Sars Abdala 
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