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ProteomicsGastrobodies are engineered antibody mimetics resilient to pepsin and hydrochloric acid
Protein-based targeting reagents, such as antibodies and non-antibody scaffold proteins, are rapidly inactivated in the upper gastrointestinal (GI) tract. Hydrochloric acid in gastric juice denatures proteins and activates pepsin, concentrations of which reach 1 mg/mL in the mammalian stomach. Here ...
ORGANISM(S): Escherichia coli 
2021-08-13 | PXD027071 | Pride
Sbti Protease Gastrobody 
TranscriptomicsSymptomatic SARS-CoV-2 breakthrough infections broaden the repertoire of Spike-reactive CD4 T cells
SARS-CoV-2 breakthrough infections (BTI) are relatively common, but little is known in terms of differentiating responses associated with asymptomatic BTI (ABTI) versus symptomatic BTI (SBTI). Here, we investigated the impact of ABTI and SBTI on antibody and T cell responses towards Spike. SBTI dono...
ORGANISM(S): Homo sapiens 
2025-12-02 | GSE311993 | GEO
UnknownSymptomatic SARS-CoV-2 breakthrough infections broaden the repertoire of Spike-reactive CD4 T cells.
Not available
S-EPMC12802171 | biostudies-literature
GenomicsSymptomatic SARS-CoV-2 breakthrough infections broaden the repertoire of Spike-reactive CD4 T cells
Symptomatic SARS-CoV-2 breakthrough infections broaden the repertoire of Spike-reactive CD4 T cells
PRJNA1372037 | ENA
UnknownGastrobodies are engineered antibody mimetics resilient to pepsin and hydrochloric acid.
Not available
S-EPMC8358037 | biostudies-literature
UnknownInvestigation into defect chemistry and relaxation processes in niobium doped and undoped SrBi4Ti4O15 using impedance spectroscopy.
Not available
S-EPMC9087022 | biostudies-literature
UnknownIdentification of Altered Metabolomic Profiles Following a Panchakarma-based Ayurvedic Intervention in Healthy Subjects: The Self-Directed Biological Transformation Initiative (SBTI).
Not available
S-EPMC5017211 | biostudies-literature
UnknownClinical significance and diagnostic usefulness of serologic markers for improvement of outcome of tonsillectomy in adults with chronic tonsillitis.
Not available
S-EPMC3701599 | biostudies-literature
UnknownGlycopolymer induction of mouse sperm acrosomal exocytosis shows highly cooperative self-antagonism.
Not available
S-EPMC4886651 | biostudies-literature
UnknownRole of protease-activated receptor-2 on cell death and DNA fragmentation in Helicobacter pylori-infected gastric epithelial cells.
Not available
S-EPMC2945981 | biostudies-literature
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